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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
15.76
Human Site:
Y317
Identified Species:
24.76
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
Y317
Q
E
A
P
L
V
L
Y
R
P
V
G
D
Q
W
Chimpanzee
Pan troglodytes
XP_514923
412
45566
Y317
Q
E
A
P
L
V
L
Y
R
P
M
G
D
Q
W
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
Y316
Q
E
A
P
L
V
L
Y
R
P
V
D
G
Q
W
Dog
Lupus familis
XP_544908
406
45137
C317
R
E
A
P
L
V
L
C
R
P
V
G
G
Q
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
W319
R
D
A
P
L
V
L
W
R
P
V
G
G
E
W
Rat
Rattus norvegicus
NP_001129139
365
40341
R279
V
F
Q
L
D
A
S
R
Q
Q
L
V
F
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
Y401
R
E
T
A
I
L
L
Y
R
P
Q
N
G
E
W
Chicken
Gallus gallus
XP_416749
417
46882
Y327
N
E
A
P
L
Q
L
Y
K
P
C
D
G
Q
W
Frog
Xenopus laevis
Q7ZY78
396
43627
K310
V
R
E
E
P
L
L
K
Y
K
E
L
D
D
Q
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
R319
D
M
K
V
L
L
Y
R
H
S
E
Q
H
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
W327
V
C
A
E
A
G
S
W
S
I
S
N
F
T
L
Honey Bee
Apis mellifera
XP_001120270
256
29743
E170
K
I
P
K
R
D
I
E
K
F
N
E
Q
L
H
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
V302
S
T
K
D
Y
F
A
V
L
G
R
S
T
V
H
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
S348
K
C
S
C
D
V
Q
S
V
F
K
G
L
H
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
N356
Q
I
I
T
F
P
Y
N
V
I
S
L
S
A
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
93.3
86.6
80
N.A.
66.6
0
N.A.
40
60
13.3
6.6
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
86.6
86.6
N.A.
93.3
20
N.A.
66.6
66.6
20
13.3
N.A.
13.3
20
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
7
7
7
7
0
0
0
0
0
0
7
0
% A
% Cys:
0
14
0
7
0
0
0
7
0
0
7
0
0
0
0
% C
% Asp:
7
7
0
7
14
7
0
0
0
0
0
14
20
7
0
% D
% Glu:
0
40
7
14
0
0
0
7
0
0
14
7
0
14
0
% E
% Phe:
0
7
0
0
7
7
0
0
0
14
0
0
14
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
7
0
34
34
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
7
7
20
% H
% Ile:
0
14
7
0
7
0
7
0
0
14
0
0
0
0
0
% I
% Lys:
14
0
14
7
0
0
0
7
14
7
7
0
0
0
7
% K
% Leu:
0
0
0
7
47
20
54
0
7
0
7
14
7
7
7
% L
% Met:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
7
0
0
7
14
0
0
0
% N
% Pro:
0
0
7
40
7
7
0
0
0
47
0
0
0
0
0
% P
% Gln:
27
0
7
0
0
7
7
0
7
7
7
7
7
34
14
% Q
% Arg:
20
7
0
0
7
0
0
14
40
0
7
0
0
7
7
% R
% Ser:
7
0
7
0
0
0
14
7
7
7
14
7
7
0
0
% S
% Thr:
0
7
7
7
0
0
0
0
0
0
0
0
7
7
0
% T
% Val:
20
0
0
7
0
40
0
7
14
0
27
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
14
0
0
0
0
0
7
47
% W
% Tyr:
0
0
0
0
7
0
14
34
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _