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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
29.09
Human Site:
Y218
Identified Species:
45.71
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
Y218
G
T
L
R
L
W
E
Y
R
S
G
R
Q
L
H
Chimpanzee
Pan troglodytes
XP_514923
412
45566
Y218
G
T
L
R
L
W
E
Y
R
S
G
R
Q
L
H
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
Y217
G
T
L
R
L
W
E
Y
R
S
G
R
Q
L
H
Dog
Lupus familis
XP_544908
406
45137
Y218
C
T
L
R
L
W
E
Y
R
G
G
R
E
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
Y220
G
T
L
R
L
W
E
Y
R
S
G
R
Q
L
Q
Rat
Rattus norvegicus
NP_001129139
365
40341
H189
I
E
A
F
C
L
G
H
T
E
F
V
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
Y302
C
S
L
R
L
W
E
Y
T
S
G
R
E
L
Q
Chicken
Gallus gallus
XP_416749
417
46882
Y228
C
T
L
R
L
W
K
Y
E
T
G
E
E
V
Y
Frog
Xenopus laevis
Q7ZY78
396
43627
E217
W
E
Y
E
S
G
K
E
V
H
S
V
T
L
R
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
Y219
G
T
V
N
V
W
H
Y
E
T
G
R
R
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
C225
T
F
D
I
H
S
Y
C
L
G
H
R
E
F
V
Honey Bee
Apis mellifera
XP_001120270
256
29743
L80
L
G
H
L
S
M
L
L
D
I
L
I
T
E
D
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
L212
A
V
Q
D
N
D
S
L
W
S
S
G
G
D
K
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
Y255
D
H
S
T
V
P
I
Y
H
I
K
T
E
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
W236
Q
C
F
I
V
D
K
W
L
F
G
H
K
H
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
100
80
N.A.
93.3
0
N.A.
66.6
46.6
6.6
53.3
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
6.6
N.A.
80
80
13.3
80
N.A.
13.3
0
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
20
7
0
0
7
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
7
0
14
0
0
7
0
0
0
0
7
14
% D
% Glu:
0
14
0
7
0
0
40
7
14
7
0
7
34
7
0
% E
% Phe:
0
7
7
7
0
0
0
0
0
7
7
0
0
7
7
% F
% Gly:
34
7
0
0
0
7
7
0
0
14
60
7
7
0
0
% G
% His:
0
7
7
0
7
0
7
7
7
7
7
7
0
7
34
% H
% Ile:
7
0
0
14
0
0
7
0
0
14
0
7
0
0
7
% I
% Lys:
0
0
0
0
0
0
20
0
0
0
7
0
7
7
7
% K
% Leu:
7
0
47
7
47
7
7
14
14
0
7
0
0
54
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
7
0
0
0
0
0
0
0
0
0
27
0
14
% Q
% Arg:
0
0
0
47
0
0
0
0
34
0
0
54
7
7
7
% R
% Ser:
0
7
7
0
14
7
7
0
0
40
14
0
7
0
0
% S
% Thr:
7
47
0
7
0
0
0
0
14
14
0
7
14
0
0
% T
% Val:
0
7
7
0
20
0
0
0
7
0
0
14
0
7
7
% V
% Trp:
7
0
0
0
0
54
0
7
7
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
7
60
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _