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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
19.7
Human Site:
T90
Identified Species:
30.95
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
T90
K
R
L
I
L
F
R
T
K
P
W
Q
C
L
S
Chimpanzee
Pan troglodytes
XP_514923
412
45566
T90
K
R
L
I
L
F
R
T
K
P
W
Q
C
L
S
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
T90
K
R
L
I
L
F
R
T
K
P
W
Q
C
L
S
Dog
Lupus familis
XP_544908
406
45137
T90
K
R
L
I
L
F
R
T
K
P
W
Q
C
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
T92
K
R
L
I
L
F
R
T
K
P
W
Q
C
L
S
Rat
Rattus norvegicus
NP_001129139
365
40341
G62
D
G
Q
P
A
D
R
G
S
D
T
I
L
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
Q174
R
L
I
L
F
R
T
Q
P
S
W
E
C
L
S
Chicken
Gallus gallus
XP_416749
417
46882
K100
H
L
I
L
F
R
T
K
P
S
W
E
C
I
S
Frog
Xenopus laevis
Q7ZY78
396
43627
I90
T
K
P
A
W
E
K
I
S
V
R
W
V
S
R
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
E91
R
L
V
L
F
C
T
E
P
S
W
K
C
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
T97
A
S
G
L
G
C
A
T
S
T
S
V
Q
N
V
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
N85
R
L
V
A
V
G
T
N
E
K
Q
I
H
V
F
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
T124
G
D
E
N
K
E
H
T
L
I
L
G
H
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
P100
S
P
G
L
G
A
P
P
I
Y
S
Y
I
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
26.6
20
0
20
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
53.3
46.6
13.3
53.3
N.A.
13.3
0
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
14
7
7
7
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
14
0
0
0
0
0
0
54
0
0
% C
% Asp:
7
7
0
0
0
7
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
14
0
7
7
0
0
14
0
0
0
% E
% Phe:
0
0
0
0
20
34
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
7
14
0
14
7
0
7
0
0
0
7
0
0
0
% G
% His:
7
0
0
0
0
0
7
0
0
0
0
0
14
0
0
% H
% Ile:
0
0
14
34
0
0
0
7
7
7
0
14
7
14
0
% I
% Lys:
34
7
0
0
7
0
7
7
34
7
0
7
0
0
0
% K
% Leu:
0
27
34
34
34
0
0
0
7
0
7
0
7
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
7
0
0
0
0
0
7
7
% N
% Pro:
0
7
7
7
0
0
7
7
20
34
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
7
0
0
7
34
7
0
0
% Q
% Arg:
20
34
0
0
0
14
40
0
0
0
7
0
0
7
7
% R
% Ser:
7
7
0
0
0
0
0
0
20
20
14
0
0
7
67
% S
% Thr:
7
0
0
0
0
0
27
47
0
7
7
0
0
0
0
% T
% Val:
0
0
14
0
7
0
0
0
0
7
0
7
7
14
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
54
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _