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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
18.79
Human Site:
T68
Identified Species:
29.52
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
T68
S
G
A
I
L
A
S
T
F
S
K
S
G
S
Y
Chimpanzee
Pan troglodytes
XP_514923
412
45566
T68
S
G
A
I
L
A
S
T
F
S
K
S
G
S
Y
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
T68
S
G
V
I
L
A
S
T
F
S
K
S
G
S
Y
Dog
Lupus familis
XP_544908
406
45137
T68
S
D
T
I
L
A
S
T
F
S
K
S
G
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
T70
S
D
S
I
L
A
S
T
F
S
K
S
G
R
Y
Rat
Rattus norvegicus
NP_001129139
365
40341
C40
D
C
L
F
S
Y
D
C
S
T
A
E
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
F152
D
N
I
L
A
S
T
F
S
K
S
G
N
F
F
Chicken
Gallus gallus
XP_416749
417
46882
F78
D
N
I
L
A
F
A
F
S
P
S
G
D
Y
F
Frog
Xenopus laevis
Q7ZY78
396
43627
Y68
A
F
S
P
S
G
E
Y
F
A
L
T
D
D
N
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
I69
D
S
I
L
A
F
A
I
S
A
S
G
K
H
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
Q75
Q
A
P
G
G
K
E
Q
Q
L
A
N
Q
P
E
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
I63
K
A
V
E
K
R
V
I
L
C
L
A
H
S
N
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
L102
F
D
N
S
E
T
A
L
Y
V
A
D
K
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
S78
N
E
N
K
K
L
K
S
N
K
G
D
S
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
93.3
86.6
N.A.
80
0
N.A.
0
0
6.6
0
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
6.6
N.A.
26.6
20
33.3
20
N.A.
6.6
0
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
14
0
20
34
20
0
0
14
20
7
0
7
0
% A
% Cys:
0
7
0
0
0
0
0
7
0
7
0
0
0
0
0
% C
% Asp:
27
20
0
0
0
0
7
0
0
0
0
14
14
7
0
% D
% Glu:
0
7
0
7
7
0
14
0
0
0
0
7
0
0
7
% E
% Phe:
7
7
0
7
0
14
0
14
40
0
0
0
0
7
14
% F
% Gly:
0
20
0
7
7
7
0
0
0
0
7
20
34
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
0
20
34
0
0
0
14
0
0
0
0
0
7
0
% I
% Lys:
7
0
0
7
14
7
7
0
0
14
34
0
20
7
7
% K
% Leu:
0
0
7
20
34
7
0
7
7
7
14
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
14
14
0
0
0
0
0
7
0
0
7
7
0
14
% N
% Pro:
0
0
7
7
0
0
0
0
0
7
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% R
% Ser:
34
7
14
7
14
7
34
7
27
34
20
34
7
34
7
% S
% Thr:
0
0
7
0
0
7
7
34
0
7
0
7
0
0
0
% T
% Val:
0
0
14
0
0
0
7
0
0
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
7
7
0
0
0
0
7
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _