KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
14.55
Human Site:
T25
Identified Species:
22.86
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
T25
G
G
S
R
F
L
A
T
S
I
A
S
S
D
D
Chimpanzee
Pan troglodytes
XP_514923
412
45566
T25
G
G
S
R
F
L
A
T
S
I
A
S
S
D
D
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
T25
G
G
S
R
F
L
A
T
S
T
A
S
S
D
D
Dog
Lupus familis
XP_544908
406
45137
T25
G
G
S
R
F
L
A
T
S
T
A
S
S
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
T27
S
R
F
L
A
F
S
T
T
G
S
D
D
D
C
Rat
Rattus norvegicus
NP_001129139
365
40341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
I109
P
S
L
I
A
P
F
I
S
S
S
D
D
V
C
Chicken
Gallus gallus
XP_416749
417
46882
R35
S
R
L
L
A
A
R
R
G
E
R
R
D
D
T
Frog
Xenopus laevis
Q7ZY78
396
43627
E25
L
G
H
R
V
G
S
E
C
C
P
F
H
L
D
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
Q26
L
V
A
V
N
L
K
Q
S
R
E
P
F
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
K32
P
D
D
L
Q
I
F
K
E
I
E
L
P
P
D
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
R20
I
A
S
G
D
L
I
R
T
F
R
I
S
E
E
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
H59
A
F
S
R
S
G
A
H
F
A
A
C
T
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
P35
L
S
F
K
Y
Q
S
P
N
H
W
E
F
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
93.3
93.3
N.A.
13.3
0
N.A.
6.6
6.6
20
13.3
N.A.
13.3
0
20
40
P-Site Similarity:
100
100
93.3
93.3
N.A.
33.3
0
N.A.
13.3
6.6
26.6
20
N.A.
20
0
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
20
7
34
0
0
7
34
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
7
0
7
0
0
14
% C
% Asp:
0
7
7
0
7
0
0
0
0
0
0
14
20
47
47
% D
% Glu:
0
0
0
0
0
0
0
7
7
7
14
7
0
7
7
% E
% Phe:
0
7
14
0
27
7
14
0
7
7
0
7
14
0
7
% F
% Gly:
27
34
0
7
0
14
0
0
7
7
0
0
0
0
7
% G
% His:
0
0
7
0
0
0
0
7
0
7
0
0
7
0
0
% H
% Ile:
7
0
0
7
0
7
7
7
0
20
0
7
0
0
0
% I
% Lys:
0
0
0
7
0
0
7
7
0
0
0
0
0
0
0
% K
% Leu:
20
0
14
20
0
40
0
0
0
0
0
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
14
0
0
0
0
7
0
7
0
0
7
7
7
7
0
% P
% Gln:
0
0
0
0
7
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
40
0
0
7
14
0
7
14
7
0
0
0
% R
% Ser:
14
14
40
0
7
0
20
0
40
7
14
27
34
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
14
14
0
0
7
0
7
% T
% Val:
0
7
0
7
7
0
0
0
0
0
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _