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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
33.94
Human Site:
T162
Identified Species:
53.33
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
T162
P
D
D
R
F
I
L
T
A
D
R
D
E
K
I
Chimpanzee
Pan troglodytes
XP_514923
412
45566
T162
A
D
D
R
F
I
L
T
A
D
R
D
E
K
I
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
T161
P
D
D
R
F
I
L
T
A
D
R
D
E
K
I
Dog
Lupus familis
XP_544908
406
45137
T162
P
D
D
R
Y
V
L
T
A
D
R
D
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
T164
P
D
D
Q
F
V
L
T
A
D
R
D
E
K
I
Rat
Rattus norvegicus
NP_001129139
365
40341
V133
G
D
V
Y
S
F
P
V
L
D
S
G
G
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
T246
P
D
D
Q
Y
I
L
T
A
D
R
D
E
K
I
Chicken
Gallus gallus
XP_416749
417
46882
T172
P
D
D
R
Y
I
L
T
A
D
R
D
E
K
I
Frog
Xenopus laevis
Q7ZY78
396
43627
E161
I
I
T
C
D
R
D
E
K
I
R
V
S
C
W
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
T163
P
D
D
K
Y
I
I
T
A
D
R
D
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
Q169
D
K
T
G
D
C
Y
Q
Y
D
C
V
E
V
E
Honey Bee
Apis mellifera
XP_001120270
256
29743
K24
Q
L
C
L
Y
E
R
K
S
Q
N
L
L
L
N
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
S156
I
E
M
A
G
A
I
S
M
I
L
D
V
A
F
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
W199
G
D
S
S
M
I
M
W
D
Y
R
E
G
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
S180
V
Y
S
I
D
I
N
S
I
P
E
E
K
F
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
93.3
100
86.6
N.A.
86.6
13.3
N.A.
86.6
93.3
6.6
80
N.A.
13.3
0
6.6
26.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
13.3
N.A.
100
100
6.6
100
N.A.
13.3
13.3
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
7
0
0
54
0
0
0
0
7
0
% A
% Cys:
0
0
7
7
0
7
0
0
0
0
7
0
0
14
0
% C
% Asp:
7
67
54
0
20
0
7
0
7
67
0
60
0
0
0
% D
% Glu:
0
7
0
0
0
7
0
7
0
0
7
14
60
0
14
% E
% Phe:
0
0
0
0
27
7
0
0
0
0
0
0
0
7
7
% F
% Gly:
14
0
0
7
7
0
0
0
0
0
0
7
14
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
7
0
7
0
54
14
0
7
14
0
0
0
0
54
% I
% Lys:
0
7
0
7
0
0
0
7
7
0
0
0
7
60
0
% K
% Leu:
0
7
0
7
0
0
47
0
7
0
7
7
7
7
0
% L
% Met:
0
0
7
0
7
0
7
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
7
% N
% Pro:
47
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% P
% Gln:
7
0
0
14
0
0
0
7
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
34
0
7
7
0
0
0
67
0
0
0
0
% R
% Ser:
0
0
14
7
7
0
0
14
7
0
7
0
7
0
0
% S
% Thr:
0
0
14
0
0
0
0
54
0
0
0
0
0
0
7
% T
% Val:
7
0
7
0
0
14
0
7
0
0
0
14
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% W
% Tyr:
0
7
0
7
34
0
7
0
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _