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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
25.15
Human Site:
T109
Identified Species:
39.52
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
T109
A
R
R
C
T
A
L
T
F
I
A
S
E
E
K
Chimpanzee
Pan troglodytes
XP_514923
412
45566
T109
A
R
R
C
T
A
L
T
F
I
A
S
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
T109
A
R
R
C
T
A
L
T
F
I
A
S
E
E
K
Dog
Lupus familis
XP_544908
406
45137
T109
V
R
R
C
T
A
L
T
F
T
A
S
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
T111
V
R
R
C
T
A
L
T
F
T
A
S
E
D
R
Rat
Rattus norvegicus
NP_001129139
365
40341
T81
S
G
R
Y
F
A
L
T
D
D
S
K
R
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
T193
V
R
R
C
T
S
L
T
F
T
T
S
E
E
K
Chicken
Gallus gallus
XP_416749
417
46882
I119
N
R
R
C
T
S
L
I
I
T
A
A
E
D
K
Frog
Xenopus laevis
Q7ZY78
396
43627
N109
L
T
F
S
P
C
G
N
H
I
L
V
A
D
K
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
A110
V
R
R
C
T
S
L
A
F
T
Q
A
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
T116
D
G
Q
L
L
A
V
T
T
S
G
K
Q
K
A
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
T104
N
D
K
G
D
I
V
T
A
E
H
I
V
T
S
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
N143
V
V
V
S
P
D
D
N
L
I
M
T
A
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
A119
S
D
E
S
R
L
I
A
C
A
D
S
D
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
100
86.6
N.A.
73.3
26.6
N.A.
73.3
53.3
13.3
46.6
N.A.
13.3
0
6.6
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
40
N.A.
80
73.3
20
73.3
N.A.
40
0
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
47
0
14
7
7
40
14
14
0
7
% A
% Cys:
0
0
0
54
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
7
7
7
0
7
7
7
0
7
27
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
7
0
0
54
40
7
% E
% Phe:
0
0
7
0
7
0
0
0
47
0
0
0
0
0
0
% F
% Gly:
0
14
0
7
0
0
7
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
7
7
7
34
0
7
0
0
7
% I
% Lys:
0
0
7
0
0
0
0
0
0
0
0
14
0
14
47
% K
% Leu:
7
0
0
7
7
7
60
0
7
0
7
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
7
0
7
0
0
% Q
% Arg:
0
54
60
0
7
0
0
0
0
0
0
0
7
0
14
% R
% Ser:
14
0
0
20
0
20
0
0
0
7
7
47
0
0
14
% S
% Thr:
0
7
0
0
54
0
0
60
7
34
7
7
0
7
0
% T
% Val:
34
7
7
0
0
0
14
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _