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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
13.99
Human Site:
S411
Identified Species:
21.98
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S411
R
P
G
E
A
T
L
S
C
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S411
R
P
G
E
A
T
L
S
C
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S410
R
P
G
E
A
T
L
S
C
_
_
_
_
_
_
Dog
Lupus familis
XP_544908
406
45137
R405
K
P
G
E
A
S
V
R
S
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
S412
C
P
G
Q
S
A
L
S
C
_
_
_
_
_
_
Rat
Rattus norvegicus
NP_001129139
365
40341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
A492
K
K
M
K
T
G
D
A
P
_
_
_
_
_
_
Chicken
Gallus gallus
XP_416749
417
46882
S415
K
K
T
K
T
E
E
S
S
L
_
_
_
_
_
Frog
Xenopus laevis
Q7ZY78
396
43627
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
C423
E
E
Q
Q
Q
Q
K
C
G
_
_
_
_
_
_
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
100
44.4
N.A.
55.5
0
N.A.
0
10
0
0
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
77.7
N.A.
77.7
0
N.A.
33.3
30
0
0
N.A.
11.1
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
27
7
0
7
0
0
0
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
7
27
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
7
7
0
27
0
7
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
34
0
0
7
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
14
0
14
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
27
0
0
7
0
0
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
34
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
7
14
7
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
7
0
34
14
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
14
20
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
47
54
54
54
54
54
% _