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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
11.21
Human Site:
S330
Identified Species:
17.62
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S330
Q
W
Q
S
V
P
E
S
T
V
L
K
K
V
S
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S330
Q
W
Q
S
V
P
E
S
A
V
L
K
K
V
S
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S329
Q
W
Q
S
V
P
E
S
A
V
L
K
K
V
S
Dog
Lupus familis
XP_544908
406
45137
N330
Q
W
Q
A
V
P
E
N
A
A
L
K
K
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
G332
E
W
Q
A
A
P
D
G
A
V
S
P
R
L
C
Rat
Rattus norvegicus
NP_001129139
365
40341
H292
R
Q
R
L
T
F
P
H
R
V
W
D
V
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
N414
E
W
Q
P
A
S
E
N
E
V
L
K
K
I
S
Chicken
Gallus gallus
XP_416749
417
46882
D340
Q
W
K
S
V
T
D
D
E
G
L
Q
R
M
S
Frog
Xenopus laevis
Q7ZY78
396
43627
N323
D
Q
W
Q
S
V
S
N
D
E
E
L
T
R
L
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
S332
W
R
L
C
D
S
E
S
P
E
L
K
K
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
Y340
T
L
T
S
D
R
I
Y
I
T
G
A
E
N
E
Honey Bee
Apis mellifera
XP_001120270
256
29743
E183
L
H
N
C
N
L
E
E
S
V
E
V
L
P
V
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
N315
V
H
L
I
D
L
N
N
M
E
Q
K
F
V
P
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
M361
H
K
V
P
F
D
N
M
S
D
Y
L
Q
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
V369
A
H
N
D
E
F
Q
V
T
L
D
N
K
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
93.3
93.3
73.3
N.A.
26.6
13.3
N.A.
53.3
40
0
40
N.A.
6.6
13.3
13.3
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
60
26.6
N.A.
73.3
73.3
6.6
46.6
N.A.
13.3
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
14
14
0
0
0
27
7
0
7
0
0
0
% A
% Cys:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
7
0
0
7
20
7
14
7
7
7
7
7
0
0
0
% D
% Glu:
14
0
0
0
7
0
47
7
14
20
14
0
7
7
7
% E
% Phe:
0
0
0
0
7
14
0
0
0
0
0
0
7
0
7
% F
% Gly:
0
0
0
0
0
0
0
7
0
7
7
0
0
0
0
% G
% His:
7
20
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
7
0
7
0
0
0
0
7
0
% I
% Lys:
0
7
7
0
0
0
0
0
0
0
0
47
47
0
7
% K
% Leu:
7
7
14
7
0
14
0
0
0
7
47
14
7
7
7
% L
% Met:
0
0
0
0
0
0
0
7
7
0
0
0
0
7
0
% M
% Asn:
0
0
14
0
7
0
14
27
0
0
0
7
0
7
0
% N
% Pro:
0
0
0
14
0
34
7
0
7
0
0
7
0
7
7
% P
% Gln:
34
14
40
7
0
0
7
0
0
0
7
7
7
0
0
% Q
% Arg:
7
7
7
0
0
7
0
0
7
0
0
0
14
14
0
% R
% Ser:
0
0
0
34
7
14
7
27
14
0
7
0
0
0
47
% S
% Thr:
7
0
7
0
7
7
0
0
14
7
0
0
7
0
7
% T
% Val:
7
0
7
0
34
7
0
7
0
47
0
7
7
47
7
% V
% Trp:
7
47
7
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _