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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
21.82
Human Site:
S207
Identified Species:
34.29
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S207
Q
P
G
L
L
L
S
S
S
G
D
G
T
L
R
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S207
Q
P
G
L
L
L
S
S
S
G
D
G
T
L
R
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S206
Q
P
G
L
L
L
S
S
S
G
D
G
T
L
R
Dog
Lupus familis
XP_544908
406
45137
S207
H
P
E
L
L
L
S
S
S
G
D
C
T
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
S209
H
P
E
L
L
L
S
S
S
G
D
G
T
L
R
Rat
Rattus norvegicus
NP_001129139
365
40341
A178
I
R
V
S
W
A
A
A
P
H
S
I
E
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
T291
C
P
D
L
L
L
S
T
S
G
D
C
S
L
R
Chicken
Gallus gallus
XP_416749
417
46882
A217
Y
P
D
L
L
L
S
A
S
G
D
C
T
L
R
Frog
Xenopus laevis
Q7ZY78
396
43627
T206
L
S
G
S
G
D
G
T
L
R
L
W
E
Y
E
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
G208
H
P
D
W
L
L
S
G
S
G
D
G
T
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
N214
D
D
K
I
R
V
T
N
Y
P
A
T
F
D
I
Honey Bee
Apis mellifera
XP_001120270
256
29743
E69
S
N
K
Q
S
D
N
E
V
L
L
L
G
H
L
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
V201
F
L
G
H
T
E
Y
V
K
T
L
A
V
Q
D
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
V244
K
E
H
N
L
V
A
V
T
V
L
D
H
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
S225
R
D
E
H
I
K
I
S
H
Y
P
Q
C
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
100
80
N.A.
86.6
0
N.A.
66.6
73.3
6.6
60
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
13.3
N.A.
80
80
13.3
66.6
N.A.
26.6
6.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
14
14
0
0
7
7
0
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
20
7
0
0
% C
% Asp:
7
14
20
0
0
14
0
0
0
0
54
7
0
7
7
% D
% Glu:
0
7
20
0
0
7
0
7
0
0
0
0
14
0
7
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% F
% Gly:
0
0
34
0
7
0
7
7
0
54
0
34
7
0
0
% G
% His:
20
0
7
14
0
0
0
0
7
7
0
0
7
7
0
% H
% Ile:
7
0
0
7
7
0
7
0
0
0
0
7
0
0
14
% I
% Lys:
7
0
14
0
0
7
0
0
7
0
0
0
0
0
0
% K
% Leu:
7
7
0
47
60
54
0
0
7
7
27
7
0
47
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
7
7
0
0
0
0
0
0
7
% N
% Pro:
0
54
0
0
0
0
0
0
7
7
7
0
0
0
0
% P
% Gln:
20
0
0
7
0
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
7
7
0
0
7
0
0
0
0
7
0
0
0
0
47
% R
% Ser:
7
7
0
14
7
0
54
40
54
0
7
0
7
7
0
% S
% Thr:
0
0
0
0
7
0
7
14
7
7
0
7
47
0
7
% T
% Val:
0
0
7
0
0
14
0
14
7
7
0
0
7
7
0
% V
% Trp:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
0
7
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _