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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
29.7
Human Site:
S172
Identified Species:
46.67
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S172
R
D
E
K
I
R
V
S
W
A
A
A
P
H
S
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S172
R
D
E
K
I
R
V
S
W
A
A
A
P
H
S
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S171
R
D
E
K
I
R
V
S
W
A
A
A
P
H
S
Dog
Lupus familis
XP_544908
406
45137
S172
R
D
E
K
I
R
V
S
W
A
A
A
P
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
S174
R
D
E
K
I
R
V
S
W
A
A
A
P
H
S
Rat
Rattus norvegicus
NP_001129139
365
40341
E143
S
G
G
C
G
R
L
E
L
G
H
L
S
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
S256
R
D
E
K
I
R
V
S
L
F
S
A
P
H
N
Chicken
Gallus gallus
XP_416749
417
46882
S182
R
D
E
K
I
R
V
S
L
T
K
A
P
Y
N
Frog
Xenopus laevis
Q7ZY78
396
43627
P171
R
V
S
C
W
G
A
P
H
V
I
M
S
F
C
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
S173
R
D
E
K
I
R
V
S
F
R
R
S
P
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
P179
C
V
E
V
E
A
P
P
R
L
L
L
G
H
L
Honey Bee
Apis mellifera
XP_001120270
256
29743
L34
N
L
L
L
N
K
I
L
P
R
A
A
S
K
V
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
D166
L
D
V
A
F
S
P
D
G
K
R
L
L
M
A
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
R209
R
E
G
K
E
L
C
R
T
S
F
E
W
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
P190
E
E
K
F
T
Q
E
P
I
L
G
H
V
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
73.3
66.6
6.6
60
N.A.
13.3
13.3
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
86.6
80
6.6
86.6
N.A.
13.3
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
7
0
0
34
40
54
0
7
7
% A
% Cys:
7
0
0
14
0
0
7
0
0
0
0
0
0
0
7
% C
% Asp:
0
60
0
0
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
7
14
60
0
14
0
7
7
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
7
7
0
0
0
7
7
7
0
0
7
0
% F
% Gly:
0
7
14
0
7
7
0
0
7
7
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
7
0
47
0
% H
% Ile:
0
0
0
0
54
0
7
0
7
0
7
0
0
0
0
% I
% Lys:
0
0
7
60
0
7
0
0
0
7
7
0
0
7
0
% K
% Leu:
7
7
7
7
0
7
7
7
20
14
7
20
7
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
14
7
% M
% Asn:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
20
% N
% Pro:
0
0
0
0
0
0
14
20
7
0
0
0
54
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
67
0
0
0
0
60
0
7
7
14
14
0
0
0
7
% R
% Ser:
7
0
7
0
0
7
0
54
0
7
7
7
20
7
34
% S
% Thr:
0
0
0
0
7
0
0
0
7
7
0
0
0
0
0
% T
% Val:
0
14
7
7
0
0
54
0
0
7
0
0
7
0
7
% V
% Trp:
0
0
0
0
7
0
0
0
34
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _