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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
23.94
Human Site:
S130
Identified Species:
37.62
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S130
S
G
D
V
Y
S
F
S
V
L
E
P
H
G
C
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S130
S
G
D
V
Y
S
F
S
V
L
E
P
H
G
C
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S130
S
G
E
E
P
S
W
S
V
L
E
G
R
V
L
Dog
Lupus familis
XP_544908
406
45137
P130
S
G
D
V
Y
S
F
P
V
L
E
P
Q
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
S132
S
G
D
V
Y
S
F
S
V
L
E
P
D
G
C
Rat
Rattus norvegicus
NP_001129139
365
40341
T102
W
Q
C
L
S
V
R
T
V
V
R
R
C
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
S214
S
G
D
V
Y
S
F
S
V
M
E
P
H
S
G
Chicken
Gallus gallus
XP_416749
417
46882
S140
S
G
D
V
Y
S
Y
S
I
T
E
P
Q
A
E
Frog
Xenopus laevis
Q7ZY78
396
43627
E130
F
S
V
P
R
A
L
E
Q
G
R
L
E
L
G
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
S131
S
G
D
V
Y
S
F
S
I
L
E
P
H
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
L137
R
P
E
N
A
R
L
L
S
A
R
P
L
A
R
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
E125
T
A
I
V
F
D
K
E
D
A
Y
V
V
V
G
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
N164
S
H
L
P
N
A
Y
N
I
H
T
F
C
M
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
L140
D
K
T
S
K
N
V
L
K
L
R
K
R
F
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
46.6
80
N.A.
93.3
6.6
N.A.
80
60
0
80
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
60
80
N.A.
93.3
26.6
N.A.
86.6
73.3
6.6
86.6
N.A.
13.3
0
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
14
0
0
0
14
0
0
0
14
14
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
14
0
34
% C
% Asp:
7
0
47
0
0
7
0
0
7
0
0
0
7
0
0
% D
% Glu:
0
0
14
7
0
0
0
14
0
0
54
0
7
0
7
% E
% Phe:
7
0
0
0
7
0
40
0
0
0
0
7
0
7
0
% F
% Gly:
0
54
0
0
0
0
0
0
0
7
0
7
0
20
27
% G
% His:
0
7
0
0
0
0
0
0
0
7
0
0
27
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
20
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
7
0
7
0
7
0
0
7
0
7
0
% K
% Leu:
0
0
7
7
0
0
14
14
0
47
0
7
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% M
% Asn:
0
0
0
7
7
7
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
14
7
0
0
7
0
0
0
54
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
7
0
0
0
14
0
0
% Q
% Arg:
7
0
0
0
7
7
7
0
0
0
27
7
14
7
7
% R
% Ser:
60
7
0
7
7
54
0
47
7
0
0
0
0
7
0
% S
% Thr:
7
0
7
0
0
0
0
7
0
7
7
0
0
7
0
% T
% Val:
0
0
7
54
0
7
7
0
47
7
0
7
7
14
0
% V
% Trp:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
47
0
14
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _