KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
29.09
Human Site:
S128
Identified Species:
45.71
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S128
D
K
S
G
D
V
Y
S
F
S
V
L
E
P
H
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S128
D
K
S
G
D
V
Y
S
F
S
V
L
E
P
H
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S128
D
K
S
G
E
E
P
S
W
S
V
L
E
G
R
Dog
Lupus familis
XP_544908
406
45137
S128
D
K
S
G
D
V
Y
S
F
P
V
L
E
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
S130
D
K
S
G
D
V
Y
S
F
S
V
L
E
P
D
Rat
Rattus norvegicus
NP_001129139
365
40341
V100
K
P
W
Q
C
L
S
V
R
T
V
V
R
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
S212
D
K
S
G
D
V
Y
S
F
S
V
M
E
P
H
Chicken
Gallus gallus
XP_416749
417
46882
S138
D
K
S
G
D
V
Y
S
Y
S
I
T
E
P
Q
Frog
Xenopus laevis
Q7ZY78
396
43627
A128
F
S
F
S
V
P
R
A
L
E
Q
G
R
L
E
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
S129
D
K
S
G
D
V
Y
S
F
S
I
L
E
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
R135
R
S
R
P
E
N
A
R
L
L
S
A
R
P
L
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
D123
A
P
T
A
I
V
F
D
K
E
D
A
Y
V
V
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
A162
R
V
S
H
L
P
N
A
Y
N
I
H
T
F
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
N138
D
V
D
K
T
S
K
N
V
L
K
L
R
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
60
86.6
N.A.
93.3
6.6
N.A.
93.3
73.3
0
93.3
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
100
73.3
86.6
N.A.
93.3
26.6
N.A.
100
86.6
6.6
100
N.A.
13.3
0
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
7
14
0
0
0
14
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
14
% C
% Asp:
60
0
7
0
47
0
0
7
0
0
7
0
0
0
7
% D
% Glu:
0
0
0
0
14
7
0
0
0
14
0
0
54
0
7
% E
% Phe:
7
0
7
0
0
0
7
0
40
0
0
0
0
7
0
% F
% Gly:
0
0
0
54
0
0
0
0
0
0
0
7
0
7
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
27
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
7
54
0
7
0
0
7
0
7
0
7
0
0
7
0
% K
% Leu:
0
0
0
0
7
7
0
0
14
14
0
47
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
7
7
7
0
7
0
0
0
0
0
% N
% Pro:
0
14
0
7
0
14
7
0
0
7
0
0
0
54
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
14
% Q
% Arg:
14
0
7
0
0
0
7
7
7
0
0
0
27
7
14
% R
% Ser:
0
14
60
7
0
7
7
54
0
47
7
0
0
0
0
% S
% Thr:
0
0
7
0
7
0
0
0
0
7
0
7
7
0
0
% T
% Val:
0
14
0
0
7
54
0
7
7
0
47
7
0
7
7
% V
% Trp:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
47
0
14
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _