KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
33.64
Human Site:
S123
Identified Species:
52.86
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
S123
K
V
L
V
A
D
K
S
G
D
V
Y
S
F
S
Chimpanzee
Pan troglodytes
XP_514923
412
45566
S123
K
V
L
V
A
D
K
S
G
D
V
Y
S
F
S
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
S123
K
V
L
V
A
D
K
S
G
E
E
P
S
W
S
Dog
Lupus familis
XP_544908
406
45137
S123
K
L
L
V
A
D
K
S
G
D
V
Y
S
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
S125
R
V
L
V
A
D
K
S
G
D
V
Y
S
F
S
Rat
Rattus norvegicus
NP_001129139
365
40341
W95
I
L
F
R
T
K
P
W
Q
C
L
S
V
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
S207
K
I
L
V
A
D
K
S
G
D
V
Y
S
F
S
Chicken
Gallus gallus
XP_416749
417
46882
S133
K
I
L
V
A
D
K
S
G
D
V
Y
S
Y
S
Frog
Xenopus laevis
Q7ZY78
396
43627
F123
K
S
G
D
V
F
S
F
S
V
P
R
A
L
E
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
S124
E
L
Y
V
A
D
K
S
G
D
V
Y
S
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
R130
A
L
L
L
Y
R
S
R
P
E
N
A
R
L
L
Honey Bee
Apis mellifera
XP_001120270
256
29743
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
T118
S
V
V
P
K
A
P
T
A
I
V
F
D
K
E
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
S157
R
D
E
K
I
R
V
S
H
L
P
N
A
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
D133
S
L
L
V
F
D
V
D
K
T
S
K
N
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
100
73.3
86.6
N.A.
93.3
0
N.A.
93.3
86.6
6.6
80
N.A.
6.6
0
13.3
6.6
P-Site Similarity:
100
100
86.6
93.3
N.A.
100
20
N.A.
100
100
13.3
93.3
N.A.
26.6
0
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
54
7
0
0
7
0
0
7
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
60
0
7
0
47
0
0
7
0
0
% D
% Glu:
7
0
7
0
0
0
0
0
0
14
7
0
0
0
14
% E
% Phe:
0
0
7
0
7
7
0
7
0
0
0
7
0
40
0
% F
% Gly:
0
0
7
0
0
0
0
0
54
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
14
0
0
7
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
47
0
0
7
7
7
54
0
7
0
0
7
0
7
0
% K
% Leu:
0
34
60
7
0
0
0
0
0
7
7
0
0
14
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
7
7
0
7
% N
% Pro:
0
0
0
7
0
0
14
0
7
0
14
7
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
14
0
0
7
0
14
0
7
0
0
0
7
7
7
0
% R
% Ser:
14
7
0
0
0
0
14
60
7
0
7
7
54
0
47
% S
% Thr:
0
0
0
0
7
0
0
7
0
7
0
0
0
0
7
% T
% Val:
0
34
7
60
7
0
14
0
0
7
54
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
0
47
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _