KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPK4
All Species:
29.7
Human Site:
T521
Identified Species:
65.33
UniProt:
P57078
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57078
NP_065690
832
91611
T521
L
S
N
R
R
G
S
T
P
L
H
M
A
V
E
Chimpanzee
Pan troglodytes
XP_001134659
786
86619
T475
L
T
N
R
R
G
S
T
P
L
H
M
A
V
E
Rhesus Macaque
Macaca mulatta
XP_001107026
786
86655
T475
L
T
N
R
R
G
S
T
P
L
H
M
A
V
E
Dog
Lupus familis
XP_544897
826
90932
T515
L
T
N
R
K
G
S
T
P
L
H
V
A
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK0
786
86594
T475
L
T
N
R
K
G
S
T
P
L
H
M
A
V
E
Rat
Rattus norvegicus
P0C8E4
606
67182
S324
G
S
F
M
D
I
A
S
T
N
T
S
N
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511321
791
87316
T475
L
T
N
K
R
G
S
T
P
L
H
V
A
I
E
Chicken
Gallus gallus
XP_416738
789
87316
K480
P
L
H
I
A
I
E
K
K
I
K
S
I
V
E
Frog
Xenopus laevis
NP_001080415
720
79835
F438
P
Q
D
V
D
L
V
F
E
G
R
S
S
L
L
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
T684
V
T
D
A
E
G
Q
T
P
L
M
L
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180763
1378
147477
T393
N
S
S
N
D
G
L
T
P
L
H
L
A
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
92.6
83.2
N.A.
84.9
23
N.A.
77.5
72.1
61.6
22
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
93.9
93.5
88.3
N.A.
89.3
38.9
N.A.
85.6
83.7
72.9
35.8
N.A.
N.A.
N.A.
N.A.
34.9
P-Site Identity:
100
93.3
93.3
80
N.A.
86.6
6.6
N.A.
73.3
13.3
0
40
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
26.6
20
66.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
10
0
0
0
0
0
73
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
28
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
64
% E
% Phe:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
73
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
64
0
0
0
0
% H
% Ile:
0
0
0
10
0
19
0
0
0
10
0
0
10
10
0
% I
% Lys:
0
0
0
10
19
0
0
10
10
0
10
0
0
10
0
% K
% Leu:
55
10
0
0
0
10
10
0
0
73
0
19
0
10
19
% L
% Met:
0
0
0
10
0
0
0
0
0
0
10
37
0
0
0
% M
% Asn:
10
0
55
10
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
19
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
46
37
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
28
10
0
0
0
55
10
0
0
0
28
10
0
10
% S
% Thr:
0
55
0
0
0
0
0
73
10
0
10
0
0
0
0
% T
% Val:
10
0
0
10
0
0
10
0
0
0
0
19
0
64
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _