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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C21orf59
All Species:
13.33
Human Site:
Y245
Identified Species:
26.67
UniProt:
P57076
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57076
NP_067077.1
290
33224
Y245
E
Q
K
Q
L
M
L
Y
Y
H
R
R
Q
E
E
Chimpanzee
Pan troglodytes
XP_531427
484
53544
Y439
E
Q
K
Q
L
M
L
Y
Y
H
R
R
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001095882
290
33146
F245
E
Q
K
Q
L
M
L
F
Y
H
R
R
Q
E
E
Dog
Lupus familis
XP_848523
290
33220
Y245
E
Q
K
Q
L
M
L
Y
Y
Q
R
R
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_080778
290
33172
F245
E
H
K
Q
L
M
L
F
Y
H
R
R
Q
E
E
Rat
Rattus norvegicus
NP_001008289
290
33225
F245
E
H
K
Q
L
M
L
F
Y
H
R
R
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006258
290
33033
Y245
E
Q
K
Q
M
M
L
Y
Y
Y
K
K
Q
E
E
Frog
Xenopus laevis
NP_001086851
290
33316
H245
E
Q
K
K
L
M
M
H
Y
Y
R
R
Q
E
E
Zebra Danio
Brachydanio rerio
Q6DRC3
290
33522
H245
E
Q
K
Q
M
M
L
H
Y
Y
K
R
Q
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZH1
291
33099
E245
L
R
R
Q
M
M
A
E
A
Y
R
R
Q
E
E
Honey Bee
Apis mellifera
XP_623297
290
33633
H245
E
R
K
Q
L
M
L
H
A
Y
R
R
Q
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784987
290
32623
H245
E
R
K
Q
M
M
L
H
A
Y
R
K
Q
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
98.9
91.3
N.A.
92.4
91
N.A.
N.A.
77.9
73
72.7
N.A.
49.1
62
N.A.
63.4
Protein Similarity:
100
56.6
99.6
96.9
N.A.
96.9
96.2
N.A.
N.A.
89.3
86.5
85.1
N.A.
71.8
77.9
N.A.
78.9
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
73.3
73.3
73.3
N.A.
46.6
66.6
N.A.
60
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
100
100
N.A.
73.3
93.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
25
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
92
0
0
0
0
0
0
9
0
0
0
0
0
100
92
% E
% Phe:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
17
0
0
0
0
0
34
0
42
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
92
9
0
0
0
0
0
0
17
17
0
0
0
% K
% Leu:
9
0
0
0
67
0
84
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
34
100
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
59
0
92
0
0
0
0
0
9
0
0
100
0
9
% Q
% Arg:
0
25
9
0
0
0
0
0
0
0
84
84
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
75
50
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _