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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSC
All Species:
9.09
Human Site:
S221
Identified Species:
20
UniProt:
P56915
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56915
NP_776248.1
257
28150
S221
K
W
R
R
Q
K
R
S
S
S
E
E
S
E
N
Chimpanzee
Pan troglodytes
NP_001074955
257
28091
S221
K
W
R
R
Q
K
R
S
S
S
E
E
S
E
N
Rhesus Macaque
Macaca mulatta
XP_001100695
259
28265
S221
K
W
R
R
Q
K
R
S
S
S
E
E
S
E
N
Dog
Lupus familis
XP_850483
183
19885
R148
R
I
R
L
R
E
E
R
V
E
V
W
F
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q02591
256
27961
R220
A
K
W
R
R
Q
K
R
S
S
S
E
E
S
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511401
166
19150
K130
R
A
K
W
R
R
Q
K
R
S
S
S
E
E
S
Chicken
Gallus gallus
P53545
245
27250
K209
R
A
K
W
R
R
Q
K
R
S
S
S
E
E
S
Frog
Xenopus laevis
P53546
243
27395
K207
R
A
K
W
R
R
Q
K
R
S
S
S
E
E
S
Zebra Danio
Brachydanio rerio
P53544
240
26963
Q204
R
R
A
K
W
R
R
Q
K
R
S
S
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54366
419
44931
C360
R
K
L
Q
E
E
Q
C
G
S
T
T
N
G
T
Honey Bee
Apis mellifera
XP_001121922
328
37140
E286
R
M
R
K
L
Q
L
E
Q
R
Q
R
A
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
31.5
N.A.
96.8
N.A.
N.A.
56.4
85.9
76.6
73.1
N.A.
26.7
27.1
N.A.
N.A.
Protein Similarity:
100
99.6
98.8
42
N.A.
97.6
N.A.
N.A.
61
90.2
84.4
80.9
N.A.
35.7
41.7
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
26.6
N.A.
N.A.
13.3
13.3
13.3
20
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
46.6
N.A.
N.A.
53.3
53.3
53.3
40
N.A.
46.6
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
10
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
0
10
19
10
10
0
10
28
37
37
64
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
28
19
28
19
0
28
10
28
10
0
0
0
0
10
0
% K
% Leu:
0
0
10
10
10
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
37
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
28
19
37
10
10
0
10
0
0
0
0
% Q
% Arg:
64
10
46
37
46
37
37
19
28
19
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
28
37
73
46
37
37
10
28
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
28
10
28
10
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _