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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS12
All Species:
13.03
Human Site:
Y543
Identified Species:
35.83
UniProt:
P56730
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56730
NP_003610.1
875
97067
Y543
V
I
C
R
Q
L
G
Y
K
G
P
A
R
A
R
Chimpanzee
Pan troglodytes
Q5G271
875
97141
Y543
V
I
C
R
Q
L
G
Y
K
G
P
A
R
A
R
Rhesus Macaque
Macaca mulatta
Q5G267
875
97168
Y543
V
I
C
R
Q
L
G
Y
K
G
P
A
R
A
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08762
761
84100
K454
P
I
H
M
D
N
V
K
C
T
G
N
E
K
A
Rat
Rattus norvegicus
Q8CIZ5
1418
155701
C887
V
V
C
R
Q
L
G
C
G
S
A
L
S
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508784
743
82001
K436
P
I
H
V
D
N
V
K
C
A
G
N
E
R
S
Chicken
Gallus gallus
XP_420637
740
81809
K433
P
I
H
V
D
N
V
K
C
T
G
S
E
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920299
823
90091
Y486
V
V
C
R
Q
L
G
Y
S
G
L
A
K
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16264
532
57801
G225
L
D
A
V
D
C
E
G
T
E
A
H
I
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.5
N.A.
N.A.
72.2
22.5
N.A.
72
70.8
N.A.
57.3
N.A.
N.A.
N.A.
N.A.
23.5
Protein Similarity:
100
99.7
98.1
N.A.
N.A.
77.8
31.8
N.A.
78.5
76.6
N.A.
71
N.A.
N.A.
N.A.
N.A.
34
P-Site Identity:
100
100
100
N.A.
N.A.
6.6
46.6
N.A.
6.6
6.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
6.6
53.3
N.A.
6.6
13.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
12
23
45
0
56
12
% A
% Cys:
0
0
56
0
0
12
0
12
34
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
45
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
12
0
0
12
0
0
34
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
56
12
12
45
34
0
0
0
0
% G
% His:
0
0
34
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
67
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
34
34
0
0
0
12
12
0
% K
% Leu:
12
0
0
0
0
56
0
0
0
0
12
12
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
34
0
0
0
0
0
23
0
0
0
% N
% Pro:
34
0
0
0
0
0
0
0
0
0
34
0
0
0
12
% P
% Gln:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
56
0
0
0
0
0
0
0
0
34
23
45
% R
% Ser:
0
0
0
0
0
0
0
0
12
12
0
12
12
0
23
% S
% Thr:
0
0
0
0
0
0
0
0
12
23
0
0
0
12
0
% T
% Val:
56
23
0
34
0
0
34
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _