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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS12
All Species:
10
Human Site:
T268
Identified Species:
27.5
UniProt:
P56730
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56730
NP_003610.1
875
97067
T268
Q
K
M
A
A
A
V
T
C
S
F
S
H
G
P
Chimpanzee
Pan troglodytes
Q5G271
875
97141
T268
Q
K
M
A
A
A
V
T
C
S
F
S
H
G
P
Rhesus Macaque
Macaca mulatta
Q5G267
875
97168
T268
Q
K
M
A
A
A
V
T
C
S
F
S
R
G
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08762
761
84100
A198
C
D
D
Q
W
D
N
A
D
A
D
V
I
C
R
Rat
Rattus norvegicus
Q8CIZ5
1418
155701
E408
N
D
V
S
Y
G
P
E
Q
T
T
D
A
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508784
743
82001
A180
C
D
D
Q
W
D
D
A
D
A
E
V
I
C
R
Chicken
Gallus gallus
XP_420637
740
81809
A177
C
D
D
Q
W
D
D
A
D
A
E
V
V
C
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920299
823
90091
S225
V
R
L
S
G
G
P
S
A
Y
E
G
R
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16264
532
57801
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.5
N.A.
N.A.
72.2
22.5
N.A.
72
70.8
N.A.
57.3
N.A.
N.A.
N.A.
N.A.
23.5
Protein Similarity:
100
99.7
98.1
N.A.
N.A.
77.8
31.8
N.A.
78.5
76.6
N.A.
71
N.A.
N.A.
N.A.
N.A.
34
P-Site Identity:
100
100
93.3
N.A.
N.A.
0
0
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
N.A.
N.A.
6.6
20
N.A.
6.6
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
34
34
0
34
12
34
0
0
12
0
0
% A
% Cys:
34
0
0
0
0
0
0
0
34
0
0
0
0
34
0
% C
% Asp:
0
45
34
0
0
34
23
0
34
0
12
12
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
34
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% F
% Gly:
0
0
0
0
12
23
0
0
0
0
0
12
0
34
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% I
% Lys:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
34
% P
% Gln:
34
0
0
34
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
0
0
23
0
34
% R
% Ser:
0
0
0
23
0
0
0
12
0
34
0
34
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
0
12
12
0
0
12
0
% T
% Val:
12
0
12
0
0
0
34
0
0
0
0
34
12
12
0
% V
% Trp:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _