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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARL4C
All Species:
30
Human Site:
Y176
Identified Species:
38.82
UniProt:
P56559
Number Species:
17
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56559
NP_005728.2
192
21487
Y176
T
E
G
M
D
K
L
Y
E
M
I
L
K
R
R
Chimpanzee
Pan troglodytes
XP_001151874
201
22430
Y176
T
E
G
M
D
K
L
Y
E
M
I
L
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001115089
405
44449
Y176
T
E
G
M
D
K
L
Y
E
M
I
L
K
R
R
Dog
Lupus familis
XP_548073
201
22148
Y184
Q
P
G
L
E
R
L
Y
E
M
I
L
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99PE9
201
22223
Y184
Q
Q
G
L
E
R
L
Y
E
M
I
L
K
R
K
Rat
Rattus norvegicus
P61214
200
22570
H183
K
E
G
L
E
K
L
H
D
M
I
I
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519864
193
21567
Y177
T
E
G
M
D
K
L
Y
E
M
I
L
K
R
R
Chicken
Gallus gallus
P26990
175
20078
D160
P
S
C
A
T
T
G
D
G
L
Y
E
G
L
T
Frog
Xenopus laevis
P51643
181
20696
L166
C
A
T
S
G
D
G
L
Y
E
G
L
D
W
L
Zebra Danio
Brachydanio rerio
NP_998413
192
21493
Y176
H
E
G
M
D
K
L
Y
E
M
I
V
K
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40946
175
19987
D160
P
S
C
A
T
S
G
D
G
L
S
E
G
L
I
Honey Bee
Apis mellifera
XP_001120491
207
22359
Y189
H
E
G
L
D
T
L
Y
Q
L
I
L
K
R
R
Nematode Worm
Caenorhab. elegans
Q10943
181
20503
L166
C
A
T
S
G
D
G
L
Y
E
G
L
D
W
L
Sea Urchin
Strong. purpuratus
XP_785283
193
21506
K176
E
D
V
L
D
T
L
K
E
I
I
D
K
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49076
181
20642
L166
C
A
T
T
G
E
G
L
Y
E
G
L
D
W
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P36397
181
20590
L166
C
A
T
S
G
E
G
L
Y
E
G
L
D
W
L
Baker's Yeast
Sacchar. cerevisiae
P11076
181
20511
L166
C
A
T
S
G
E
G
L
Y
E
G
L
E
W
L
Red Bread Mold
Neurospora crassa
Q7RVM2
185
20961
F170
A
T
T
G
D
G
L
F
E
G
L
D
W
L
S
Conservation
Percent
Protein Identity:
100
95.5
47.4
55.7
N.A.
56.7
68.5
N.A.
97.9
42.7
45.8
95.3
N.A.
42.7
57.4
45.3
53.8
Protein Similarity:
100
95.5
47.4
78.1
N.A.
79
86
N.A.
98.9
60.4
64
96.8
N.A.
63
72.4
63.5
70.9
P-Site Identity:
100
100
100
60
N.A.
60
60
N.A.
100
0
6.6
86.6
N.A.
0
66.6
6.6
40
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
100
6.6
6.6
93.3
N.A.
6.6
86.6
6.6
60
Percent
Protein Identity:
N.A.
45.8
N.A.
46.3
43.7
46.3
Protein Similarity:
N.A.
61.9
N.A.
61.9
61.4
63
P-Site Identity:
N.A.
6.6
N.A.
6.6
6.6
20
P-Site Similarity:
N.A.
13.3
N.A.
13.3
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
28
0
12
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
28
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
45
12
0
12
6
0
0
12
23
0
0
% D
% Glu:
6
39
0
0
17
17
0
0
50
28
0
12
6
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
6
28
6
39
0
12
6
28
0
12
0
0
% G
% His:
12
0
0
0
0
0
0
6
0
0
0
0
0
6
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
6
56
6
0
0
6
% I
% Lys:
6
0
0
0
0
34
0
6
0
0
0
0
56
0
12
% K
% Leu:
0
0
0
28
0
0
62
28
0
17
6
67
0
17
28
% L
% Met:
0
0
0
28
0
0
0
0
0
45
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
0
0
0
0
50
45
% R
% Ser:
0
12
0
23
0
6
0
0
0
0
6
0
0
0
6
% S
% Thr:
23
6
34
6
12
17
0
0
0
0
0
0
0
0
6
% T
% Val:
0
0
6
0
0
0
0
0
0
0
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
6
28
0
% W
% Tyr:
0
0
0
0
0
0
0
45
28
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _