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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1S2
All Species:
40.91
Human Site:
Y86
Identified Species:
64.29
UniProt:
P56377
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56377
NP_003907.3
157
18615
Y86
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Chimpanzee
Pan troglodytes
XP_001138231
185
21159
I108
S
L
Y
F
C
C
A
I
E
D
Q
D
N
E
L
Rhesus Macaque
Macaca mulatta
XP_001102358
160
19119
Y86
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Dog
Lupus familis
XP_854230
349
39164
Y275
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
Y86
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Rat
Rattus norvegicus
P62744
142
16999
N77
C
V
D
V
N
D
N
N
L
A
Y
L
E
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006261
157
18595
Y86
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Frog
Xenopus laevis
NP_001088344
160
18927
Y86
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Zebra Danio
Brachydanio rerio
NP_991121
157
18590
Y86
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651198
157
18555
Y87
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504559
157
18615
Y87
T
L
E
V
I
H
R
Y
V
E
L
L
D
K
Y
Sea Urchin
Strong. purpuratus
XP_001203214
158
18892
Y87
T
L
E
I
I
H
R
Y
V
E
L
L
D
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
F67
R
R
Y
A
G
L
F
F
S
I
C
V
D
I
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35181
156
18134
R89
L
T
L
E
I
I
H
R
F
V
E
T
M
D
T
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
E78
C
V
D
T
N
D
N
E
L
A
Y
L
E
A
I
Conservation
Percent
Protein Identity:
100
77.3
90.6
44.9
N.A.
98.1
44.5
N.A.
N.A.
99.3
96.8
92.3
N.A.
82.1
N.A.
78.9
81
Protein Similarity:
100
77.8
91.2
44.9
N.A.
98.1
63.6
N.A.
N.A.
100
97.5
98
N.A.
88.5
N.A.
87.2
88.6
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
N.A.
100
100
100
N.A.
100
N.A.
93.3
100
P-Site Similarity:
100
33.3
100
100
N.A.
100
40
N.A.
N.A.
100
100
100
N.A.
100
N.A.
100
100
Percent
Protein Identity:
N.A.
41.4
N.A.
N.A.
54.1
48.4
Protein Similarity:
N.A.
60.5
N.A.
N.A.
73.2
66.2
P-Site Identity:
N.A.
6.6
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
20
N.A.
N.A.
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
7
0
0
14
0
0
0
14
0
% A
% Cys:
14
0
0
0
7
7
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
14
0
0
14
0
0
0
7
0
7
74
7
0
% D
% Glu:
0
0
67
7
0
0
0
7
7
67
7
0
14
7
0
% E
% Phe:
0
0
0
7
0
0
7
7
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
67
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
60
74
7
0
7
0
7
0
0
0
7
14
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% K
% Leu:
7
74
7
0
0
7
0
0
14
0
67
80
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
14
0
14
7
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
7
7
0
0
0
0
67
7
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% S
% Thr:
67
7
0
7
0
0
0
0
0
0
0
7
0
0
14
% T
% Val:
0
14
0
14
0
0
0
0
67
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
0
0
0
67
0
0
14
0
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _