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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1S2
All Species:
33.33
Human Site:
S47
Identified Species:
52.38
UniProt:
P56377
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56377
NP_003907.3
157
18615
S47
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Chimpanzee
Pan troglodytes
XP_001138231
185
21159
T69
D
K
E
K
K
K
I
T
R
E
L
V
Q
T
V
Rhesus Macaque
Macaca mulatta
XP_001102358
160
19119
S47
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Dog
Lupus familis
XP_854230
349
39164
S236
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
S47
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Rat
Rattus norvegicus
P62744
142
16999
V38
L
I
E
E
V
H
A
V
V
T
V
R
D
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006261
157
18595
S47
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Frog
Xenopus laevis
NP_001088344
160
18927
S47
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Zebra Danio
Brachydanio rerio
NP_991121
157
18590
S47
A
R
K
P
K
M
C
S
F
L
E
W
R
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651198
157
18555
S48
A
R
K
P
K
M
C
S
F
L
E
W
K
D
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504559
157
18615
A48
A
R
K
P
K
M
C
A
F
L
E
Y
K
D
L
Sea Urchin
Strong. purpuratus
XP_001203214
158
18892
N48
T
R
K
P
K
M
C
N
F
L
E
W
R
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
K28
V
P
L
E
D
S
E
K
H
K
V
E
Y
E
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35181
156
18134
N50
A
R
K
P
K
M
C
N
I
I
E
Y
N
D
H
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
V39
K
G
E
I
H
R
L
V
A
P
R
D
Q
K
Y
Conservation
Percent
Protein Identity:
100
77.3
90.6
44.9
N.A.
98.1
44.5
N.A.
N.A.
99.3
96.8
92.3
N.A.
82.1
N.A.
78.9
81
Protein Similarity:
100
77.8
91.2
44.9
N.A.
98.1
63.6
N.A.
N.A.
100
97.5
98
N.A.
88.5
N.A.
87.2
88.6
P-Site Identity:
100
6.6
100
100
N.A.
100
0
N.A.
N.A.
100
100
100
N.A.
86.6
N.A.
80
80
P-Site Similarity:
100
40
100
100
N.A.
100
6.6
N.A.
N.A.
100
100
100
N.A.
93.3
N.A.
100
86.6
Percent
Protein Identity:
N.A.
41.4
N.A.
N.A.
54.1
48.4
Protein Similarity:
N.A.
60.5
N.A.
N.A.
73.2
66.2
P-Site Identity:
N.A.
0
N.A.
N.A.
60
0
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
80
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
0
0
7
7
7
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
74
0
0
0
0
0
0
0
7
% C
% Asp:
7
0
0
0
7
0
0
0
0
0
0
7
7
74
0
% D
% Glu:
0
0
20
14
0
0
7
0
0
7
74
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
7
0
0
7
0
0
0
0
0
7
% H
% Ile:
0
7
0
7
0
0
7
0
7
7
0
0
0
0
0
% I
% Lys:
7
7
74
7
80
7
0
7
0
7
0
0
14
7
7
% K
% Leu:
7
0
7
0
0
0
7
0
0
67
7
0
0
0
54
% L
% Met:
0
0
0
0
0
74
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
14
0
0
0
0
7
0
0
% N
% Pro:
0
7
0
74
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% Q
% Arg:
0
74
0
0
0
7
0
0
7
0
7
7
54
0
0
% R
% Ser:
0
0
0
0
0
7
0
54
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
7
0
7
0
0
0
7
0
% T
% Val:
7
0
0
0
7
0
0
14
7
0
14
7
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
14
7
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _