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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHP2L1 All Species: 48.18
Human Site: S110 Identified Species: 70.67
UniProt: P55769 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55769 NP_001003796.1 128 14174 S110 S V T I K E G S Q L K Q Q I Q
Chimpanzee Pan troglodytes XP_515161 272 30171 S254 S V T I K E G S Q L K Q Q I Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CRB2 153 17229 Y135 M V K P H E E Y Q E T Y D K C
Rat Rattus norvegicus XP_001053559 128 14190 S110 S V T I K E G S Q L K Q Q I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507848 129 14087 S111 S V T I K E G S Q L K P Q I Q
Chicken Gallus gallus XP_416225 128 14056 S110 S I T I K E G S Q L K P Q I Q
Frog Xenopus laevis Q5XH16 128 14050 S110 S V T I K E G S Q L K P Q I Q
Zebra Danio Brachydanio rerio Q6PBV6 150 16670 Y132 M I K P H D E Y K E A Y D E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U3Z7 127 13865 S109 S V T T N E G S Q L K S Q I T
Honey Bee Apis mellifera XP_396907 127 13911 S109 S V T V N E G S Q L K P Q I Q
Nematode Worm Caenorhab. elegans Q21568 128 13983 S110 S I T Q N E G S Q L K S Q I Q
Sea Urchin Strong. purpuratus XP_792122 127 13896 S109 S V T T N E G S Q L K P Q I L
Poplar Tree Populus trichocarpa XP_002326012 128 13856 S110 S V T T N E G S Q L K T Q I Q
Maize Zea mays NP_001152403 127 13728 S109 S V T S N E G S Q L K Q Q I Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEY9 156 16930 K126 L V M L K P A K G D L T A E E
Baker's Yeast Sacchar. cerevisiae P39990 126 13550 S108 S I T T N D A S A I K T Q I Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47 N.A. N.A. N.A. 29.4 94.5 N.A. 95.3 92.9 92.9 31.3 N.A. 78.1 85.9 77.3 81.2
Protein Similarity: 100 47 N.A. N.A. N.A. 49.6 96 N.A. 96.1 97.6 96 52 N.A. 90.6 93.7 89.8 91.4
P-Site Identity: 100 100 N.A. N.A. N.A. 20 100 N.A. 93.3 86.6 93.3 0 N.A. 73.3 80 73.3 73.3
P-Site Similarity: 100 100 N.A. N.A. N.A. 20 100 N.A. 93.3 93.3 93.3 20 N.A. 73.3 86.6 80 73.3
Percent
Protein Identity: 78.9 79.6 N.A. 32 69.5 N.A.
Protein Similarity: 87.5 89.8 N.A. 50.6 85.1 N.A.
P-Site Identity: 80 86.6 N.A. 13.3 40 N.A.
P-Site Similarity: 80 86.6 N.A. 26.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 13 0 7 0 7 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 0 0 0 0 0 13 0 0 0 7 0 0 13 0 0 % D
% Glu: 0 0 0 0 0 82 13 0 0 13 0 0 0 13 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 75 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 25 0 38 0 0 0 0 0 7 0 0 0 82 0 % I
% Lys: 0 0 13 0 44 0 0 7 7 0 82 0 0 7 0 % K
% Leu: 7 0 0 7 0 0 0 0 0 75 7 0 0 0 7 % L
% Met: 13 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 13 0 7 0 0 0 0 0 32 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 82 0 0 25 82 0 63 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 82 0 0 7 0 0 0 82 0 0 0 13 0 0 0 % S
% Thr: 0 0 82 25 0 0 0 0 0 0 7 19 0 0 7 % T
% Val: 0 75 0 7 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 13 0 0 0 13 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _