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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT2
All Species:
26.97
Human Site:
Y258
Identified Species:
49.44
UniProt:
P55345
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55345
NP_001526.2
433
49042
Y258
P
C
S
A
D
K
D
Y
R
S
K
V
L
F
W
Chimpanzee
Pan troglodytes
XP_001161092
433
48995
Y258
P
C
S
A
D
K
D
Y
R
S
K
V
L
F
W
Rhesus Macaque
Macaca mulatta
XP_001096450
433
49207
Y258
P
C
S
A
D
K
D
Y
R
S
K
V
L
F
W
Dog
Lupus familis
XP_537926
640
71811
Y465
P
C
S
A
D
R
D
Y
R
S
K
V
L
F
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9R144
448
50458
Y270
P
C
S
A
E
K
D
Y
H
S
K
V
L
F
W
Rat
Rattus norvegicus
Q63009
353
40504
T183
D
R
A
T
L
Y
V
T
A
I
E
D
R
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513883
470
53922
Y271
P
C
N
A
D
R
D
Y
Q
K
K
V
L
F
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EZ3
340
37897
R170
F
I
A
P
I
N
D
R
V
V
E
S
R
L
D
Zebra Danio
Brachydanio rerio
Q6NWG4
349
39232
R177
N
D
V
V
V
E
G
R
L
D
F
W
S
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786231
282
31591
Y112
D
D
E
Y
F
G
S
Y
S
T
L
K
L
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142360
403
44948
A233
M
S
S
M
M
P
L
A
K
L
C
A
F
M
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
T220
D
K
A
S
L
H
L
T
A
I
E
D
S
E
Y
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
Y178
A
G
L
E
D
S
Q
Y
K
D
E
K
L
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
61.5
N.A.
77.4
29.3
N.A.
67
N.A.
30
30.7
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
98.8
65.1
N.A.
84.8
48
N.A.
78.3
N.A.
43.4
45
N.A.
N.A.
N.A.
N.A.
42.4
P-Site Identity:
100
100
100
93.3
N.A.
86.6
0
N.A.
73.3
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
93.3
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
30.4
N.A.
31.4
30
N.A.
Protein Similarity:
N.A.
49.4
N.A.
50.1
48.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
47
0
0
0
8
16
0
0
8
0
0
0
% A
% Cys:
0
47
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
24
16
0
0
47
0
54
0
0
16
0
16
0
0
8
% D
% Glu:
0
0
8
8
8
8
0
0
0
0
31
0
0
8
8
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
8
0
8
47
0
% F
% Gly:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
16
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
31
0
0
16
8
47
16
0
0
0
% K
% Leu:
0
0
8
0
16
0
16
0
8
8
8
0
62
8
0
% L
% Met:
8
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
47
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
0
16
8
% Q
% Arg:
0
8
0
0
0
16
0
16
31
0
0
0
16
0
0
% R
% Ser:
0
8
47
8
0
8
8
0
8
39
0
8
16
0
0
% S
% Thr:
0
0
0
8
0
0
0
16
0
8
0
0
0
8
0
% T
% Val:
0
0
8
8
8
0
8
0
8
8
0
47
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
47
% W
% Tyr:
0
0
0
8
0
8
0
62
0
0
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _