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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT2
All Species:
17.88
Human Site:
S421
Identified Species:
32.78
UniProt:
P55345
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55345
NP_001526.2
433
49042
S421
T
S
R
Q
D
P
T
S
Q
K
V
G
E
K
V
Chimpanzee
Pan troglodytes
XP_001161092
433
48995
S421
T
S
R
Q
D
P
T
S
Q
K
V
G
E
K
V
Rhesus Macaque
Macaca mulatta
XP_001096450
433
49207
S421
T
S
R
Q
D
P
T
S
Q
K
V
G
E
K
V
Dog
Lupus familis
XP_537926
640
71811
S628
T
S
T
Q
D
P
T
S
Q
K
V
G
E
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R144
448
50458
V433
H
V
R
T
R
S
H
V
S
T
E
L
E
T
G
Rat
Rattus norvegicus
Q63009
353
40504
C346
G
Q
L
C
E
L
S
C
S
T
D
Y
R
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513883
470
53922
S434
T
S
K
Q
D
P
D
S
Q
K
A
K
A
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EZ3
340
37897
T333
I
G
G
G
L
R
R
T
K
H
F
H
M
G
T
Zebra Danio
Brachydanio rerio
Q6NWG4
349
39232
S340
K
K
H
S
K
S
F
S
I
P
D
Q
Y
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786231
282
31591
G275
H
F
W
D
S
V
C
G
L
D
Y
S
I
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142360
403
44948
Y396
Y
F
T
G
D
Q
W
Y
V
K
E
S
V
M
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
R383
G
Q
H
C
K
I
S
R
T
Q
H
Y
K
M
R
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
N341
G
N
S
R
S
R
K
N
E
G
S
Y
L
M
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
61.5
N.A.
77.4
29.3
N.A.
67
N.A.
30
30.7
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
98.8
65.1
N.A.
84.8
48
N.A.
78.3
N.A.
43.4
45
N.A.
N.A.
N.A.
N.A.
42.4
P-Site Identity:
100
100
100
93.3
N.A.
13.3
0
N.A.
53.3
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
66.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
30.4
N.A.
31.4
30
N.A.
Protein Similarity:
N.A.
49.4
N.A.
50.1
48.5
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
16
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
47
0
8
0
0
8
16
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
16
0
39
0
8
% E
% Phe:
0
16
0
0
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
24
8
8
16
0
0
0
8
0
8
0
31
0
8
8
% G
% His:
16
0
16
0
0
0
8
0
0
8
8
8
0
0
8
% H
% Ile:
8
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% I
% Lys:
8
8
8
0
16
0
8
0
8
47
0
8
8
31
0
% K
% Leu:
0
0
8
0
8
8
0
0
8
0
0
8
8
24
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
31
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
39
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
16
0
39
0
8
0
0
39
8
0
8
0
0
0
% Q
% Arg:
0
0
31
8
8
16
8
8
0
0
0
0
8
0
31
% R
% Ser:
0
39
8
8
16
16
16
47
16
0
8
16
0
0
0
% S
% Thr:
39
0
16
8
0
0
31
8
8
16
0
0
0
8
8
% T
% Val:
0
8
0
0
0
8
0
8
8
0
31
0
8
0
31
% V
% Trp:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
8
24
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _