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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT2
All Species:
18.79
Human Site:
S253
Identified Species:
34.44
UniProt:
P55345
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55345
NP_001526.2
433
49042
S253
A
L
H
L
V
P
C
S
A
D
K
D
Y
R
S
Chimpanzee
Pan troglodytes
XP_001161092
433
48995
S253
A
L
H
L
V
P
C
S
A
D
K
D
Y
R
S
Rhesus Macaque
Macaca mulatta
XP_001096450
433
49207
S253
A
L
H
L
V
P
C
S
A
D
K
D
Y
R
S
Dog
Lupus familis
XP_537926
640
71811
S460
A
L
H
L
V
P
C
S
A
D
R
D
Y
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R144
448
50458
S265
A
L
H
L
V
P
C
S
A
E
K
D
Y
H
S
Rat
Rattus norvegicus
Q63009
353
40504
A178
G
L
I
F
P
D
R
A
T
L
Y
V
T
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513883
470
53922
N266
A
L
H
L
A
P
C
N
A
D
R
D
Y
Q
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EZ3
340
37897
A165
S
A
A
D
L
F
I
A
P
I
N
D
R
V
V
Zebra Danio
Brachydanio rerio
Q6NWG4
349
39232
V172
Y
I
A
P
I
N
D
V
V
V
E
G
R
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786231
282
31591
E107
K
P
D
W
Q
D
D
E
Y
F
G
S
Y
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001142360
403
44948
S228
V
Y
G
I
K
M
S
S
M
M
P
L
A
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
A215
G
V
V
L
P
D
K
A
S
L
H
L
T
A
I
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
L173
C
S
I
H
L
A
G
L
E
D
S
Q
Y
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
61.5
N.A.
77.4
29.3
N.A.
67
N.A.
30
30.7
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
98.8
65.1
N.A.
84.8
48
N.A.
78.3
N.A.
43.4
45
N.A.
N.A.
N.A.
N.A.
42.4
P-Site Identity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
66.6
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
86.6
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
30.4
N.A.
31.4
30
N.A.
Protein Similarity:
N.A.
49.4
N.A.
50.1
48.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
8
16
0
8
8
0
24
47
0
0
0
8
16
0
% A
% Cys:
8
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
24
16
0
0
47
0
54
0
0
16
% D
% Glu:
0
0
0
0
0
0
0
8
8
8
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
16
0
8
0
0
0
8
0
0
0
8
8
0
0
0
% G
% His:
0
0
47
8
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
8
16
8
8
0
8
0
0
8
0
0
0
0
16
% I
% Lys:
8
0
0
0
8
0
8
0
0
0
31
0
0
16
8
% K
% Leu:
0
54
0
54
16
0
0
8
0
16
0
16
0
8
8
% L
% Met:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
8
16
47
0
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
16
0
16
31
0
% R
% Ser:
8
8
0
0
0
0
8
47
8
0
8
8
0
8
39
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
16
0
8
% T
% Val:
8
8
8
0
39
0
0
8
8
8
0
8
0
8
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
8
0
8
0
62
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _