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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRPF1
All Species:
18.18
Human Site:
S490
Identified Species:
36.36
UniProt:
P55201
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55201
NP_001003694.1
1214
137499
S490
V
K
K
A
K
A
K
S
R
I
K
M
K
K
A
Chimpanzee
Pan troglodytes
XP_001139344
1189
133195
L492
L
S
R
N
G
A
P
L
L
R
R
L
Q
S
S
Rhesus Macaque
Macaca mulatta
XP_001093928
1214
137524
S490
V
K
K
A
K
A
K
S
R
I
K
M
K
K
A
Dog
Lupus familis
XP_861729
1214
137470
S490
V
K
K
A
K
A
K
S
R
I
K
M
K
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6IE82
823
93436
H185
H
C
H
E
N
M
N
H
A
I
E
T
V
E
G
Rat
Rattus norvegicus
XP_001054156
1212
137277
S489
V
K
K
A
K
A
K
S
R
I
K
M
K
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026635
1218
137679
S497
V
K
K
A
K
A
K
S
R
I
K
M
K
K
A
Frog
Xenopus laevis
Q6GQJ2
827
94374
E190
M
N
H
A
I
E
T
E
E
G
L
G
I
E
Y
Zebra Danio
Brachydanio rerio
Q803A0
829
94529
E192
T
E
E
G
L
G
I
E
Y
D
E
D
V
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20318
1042
117625
I405
P
T
L
M
K
S
M
I
S
T
I
C
V
E
R
Sea Urchin
Strong. purpuratus
XP_001190303
1270
142629
A484
S
R
K
N
M
R
K
A
R
K
I
L
A
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12311
748
86011
R111
K
K
N
P
Y
C
V
R
F
N
E
S
F
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.7
99.8
99.1
N.A.
23.2
98.1
N.A.
N.A.
91.1
23.7
23.6
N.A.
N.A.
N.A.
22.5
55
Protein Similarity:
100
64.1
99.8
99.4
N.A.
37.4
99
N.A.
N.A.
94.4
37.4
37.8
N.A.
N.A.
N.A.
40.2
68.5
P-Site Identity:
100
6.6
100
100
N.A.
6.6
100
N.A.
N.A.
100
6.6
0
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
46.6
100
100
N.A.
20
100
N.A.
N.A.
100
20
20
N.A.
N.A.
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
50
0
9
9
0
0
0
9
0
42
% A
% Cys:
0
9
0
0
0
9
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% D
% Glu:
0
9
9
9
0
9
0
17
9
0
25
0
0
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
0
0
9
9
9
0
0
0
9
0
9
0
0
9
% G
% His:
9
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
9
0
50
17
0
9
9
0
% I
% Lys:
9
50
50
0
50
0
50
0
0
9
42
0
42
42
9
% K
% Leu:
9
0
9
0
9
0
0
9
9
0
9
17
0
0
0
% L
% Met:
9
0
0
9
9
9
9
0
0
0
0
42
0
0
0
% M
% Asn:
0
9
9
17
9
0
9
0
0
9
0
0
0
0
0
% N
% Pro:
9
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
9
9
0
0
9
0
9
50
9
9
0
0
0
9
% R
% Ser:
9
9
0
0
0
9
0
42
9
0
0
9
0
9
17
% S
% Thr:
9
9
0
0
0
0
9
0
0
9
0
9
0
0
0
% T
% Val:
42
0
0
0
0
0
9
0
0
0
0
0
25
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _