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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR1H2 All Species: 13.94
Human Site: T29 Identified Species: 25.56
UniProt: P55055 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P55055 NP_009052.3 461 51102 T29 G A P S S S P T V K E E G P E
Chimpanzee Pan troglodytes XP_512838 512 55356 T29 G A P S S S P T V K E E G P E
Rhesus Macaque Macaca mulatta XP_001115995 461 51038 T29 G A P S S S P T V K E E G P E
Dog Lupus familis XP_851316 455 50496 A29 S A P S S S P A I K E E G P E
Cat Felis silvestris
Mouse Mus musculus Q60644 446 49701 K30 S A T S P T I K E E G Q E T D
Rat Rattus norvegicus Q62755 446 49717 K30 S S T S P T I K E E G Q E T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517956 624 68359 S72 G V R P A A E S L R F Q P W L
Chicken Gallus gallus NP_989873 409 47037 F29 E E E G L S L F S G S E N P P
Frog Xenopus laevis P28699 476 53015 F29 F P P S V Y P F A F S G G I R
Zebra Danio Brachydanio rerio Q9PTN2 453 50848 S31 R V N G D A T S V M D L M A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P34021 878 93835 S40 S G V N M S P S S L D S H D Y
Honey Bee Apis mellifera NP_001091685 629 66768 G76 A V A G T A G G A L F P G M A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123279 490 55735 R38 M L P Q S T G R P Y S Q S P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.9 98.6 93.9 N.A. 88 88.9 N.A. 51.5 63.7 24.3 32.3 N.A. 23.2 32.1 N.A. 38.9
Protein Similarity: 100 79.3 98.9 95.6 N.A. 90.8 90.8 N.A. 60 73.2 40.7 53.4 N.A. 33.9 45.9 N.A. 56.5
P-Site Identity: 100 100 100 80 N.A. 13.3 6.6 N.A. 6.6 20 26.6 6.6 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 100 100 86.6 N.A. 40 40 N.A. 46.6 20 26.6 26.6 N.A. 33.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 39 8 0 8 24 0 8 16 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 16 0 0 8 16 % D
% Glu: 8 8 8 0 0 0 8 0 16 16 31 39 16 0 31 % E
% Phe: 8 0 0 0 0 0 0 16 0 8 16 0 0 0 0 % F
% Gly: 31 8 0 24 0 0 16 8 0 8 16 8 47 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 16 0 8 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 16 0 31 0 0 0 0 0 % K
% Leu: 0 8 0 0 8 0 8 0 8 16 0 8 0 0 8 % L
% Met: 8 0 0 0 8 0 0 0 0 8 0 0 8 8 0 % M
% Asn: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 8 47 8 16 0 47 0 8 0 0 8 8 47 8 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 31 0 0 0 % Q
% Arg: 8 0 8 0 0 0 0 8 0 8 0 0 0 0 8 % R
% Ser: 31 8 0 54 39 47 0 24 16 0 24 8 8 0 8 % S
% Thr: 0 0 16 0 8 24 8 24 0 0 0 0 0 16 0 % T
% Val: 0 24 8 0 8 0 0 0 31 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _