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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR1H2
All Species:
0
Human Site:
S178
Identified Species:
0
UniProt:
P55055
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55055
NP_009052.3
461
51102
S178
R
K
Q
Q
Q
Q
E
S
Q
S
Q
S
Q
S
P
Chimpanzee
Pan troglodytes
XP_512838
512
55356
Rhesus Macaque
Macaca mulatta
XP_001115995
461
51038
Dog
Lupus familis
XP_851316
455
50496
Cat
Felis silvestris
Mouse
Mus musculus
Q60644
446
49701
Rat
Rattus norvegicus
Q62755
446
49717
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517956
624
68359
Chicken
Gallus gallus
NP_989873
409
47037
Frog
Xenopus laevis
P28699
476
53015
Zebra Danio
Brachydanio rerio
Q9PTN2
453
50848
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34021
878
93835
Honey Bee
Apis mellifera
NP_001091685
629
66768
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123279
490
55735
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.9
98.6
93.9
N.A.
88
88.9
N.A.
51.5
63.7
24.3
32.3
N.A.
23.2
32.1
N.A.
38.9
Protein Similarity:
100
79.3
98.9
95.6
N.A.
90.8
90.8
N.A.
60
73.2
40.7
53.4
N.A.
33.9
45.9
N.A.
56.5
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% P
% Gln:
0
0
100
100
100
100
0
0
100
0
100
0
100
0
0
% Q
% Arg:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
100
0
100
0
100
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _