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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF5
All Species:
50.61
Human Site:
Y362
Identified Species:
69.58
UniProt:
P55010
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55010
NP_001960.2
431
49223
Y362
S
E
K
A
S
K
K
Y
V
S
K
E
L
A
K
Chimpanzee
Pan troglodytes
XP_001135628
431
49234
Y362
S
E
K
A
S
K
K
Y
V
S
K
E
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001086107
510
58170
Y441
S
E
K
A
S
K
K
Y
V
S
K
E
L
A
K
Dog
Lupus familis
XP_854659
425
48689
Y356
S
E
K
A
S
K
K
Y
V
S
K
D
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P59325
429
48950
Y360
S
E
K
A
S
K
K
Y
V
S
K
E
L
A
K
Rat
Rattus norvegicus
Q07205
429
48936
Y360
S
E
K
A
S
K
K
Y
V
S
K
E
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507766
428
48873
Y359
S
E
K
A
S
K
K
Y
V
S
K
E
L
A
K
Chicken
Gallus gallus
NP_001006488
430
49060
Y360
A
E
K
A
S
K
K
Y
V
S
K
E
L
G
K
Frog
Xenopus laevis
NP_001080311
434
49605
Y358
A
E
K
P
S
K
K
Y
V
S
K
E
L
A
K
Zebra Danio
Brachydanio rerio
NP_955885
429
49090
Y355
A
E
K
V
S
K
K
Y
V
S
K
E
L
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXK6
464
51681
H385
A
Q
K
V
S
K
R
H
V
S
K
N
I
A
A
Honey Bee
Apis mellifera
XP_392511
454
50921
Y376
S
N
K
V
T
K
K
Y
V
S
K
D
L
S
Q
Nematode Worm
Caenorhab. elegans
Q22918
436
48768
Y349
G
E
K
P
S
S
K
Y
V
S
K
S
F
A
K
Sea Urchin
Strong. purpuratus
XP_787853
423
47400
Y348
A
A
K
P
S
K
K
Y
V
S
K
E
V
M
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P55876
451
48894
K385
A
I
E
A
F
G
G
K
C
N
P
E
A
L
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8F1
439
48604
E382
F
C
M
K
A
S
A
E
A
A
K
E
V
A
L
Baker's Yeast
Sacchar. cerevisiae
P38431
405
45243
L350
L
P
K
I
L
V
Q
L
Y
N
N
D
I
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
75.8
93
N.A.
97.2
96.9
N.A.
94.9
92.8
83.4
76
N.A.
50.2
53.2
49.3
52.4
Protein Similarity:
100
99.7
80.1
95.1
N.A.
98.3
98.3
N.A.
97.6
96.7
91.9
89.5
N.A.
68
70.9
65.3
71.2
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
100
86.6
86.6
86.6
N.A.
46.6
60
66.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
93.3
N.A.
80
86.6
66.6
80
Percent
Protein Identity:
N.A.
30.3
N.A.
28.7
35.2
N.A.
Protein Similarity:
N.A.
46.7
N.A.
47.3
53.1
N.A.
P-Site Identity:
N.A.
20
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
6
0
53
6
0
6
0
6
6
0
0
6
71
6
% A
% Cys:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
18
0
0
0
% D
% Glu:
0
65
6
0
0
0
0
6
0
0
0
71
0
0
0
% E
% Phe:
6
0
0
0
6
0
0
0
0
0
0
0
6
0
0
% F
% Gly:
6
0
0
0
0
6
6
0
0
0
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
6
0
0
0
0
0
0
0
0
12
6
0
% I
% Lys:
0
0
89
6
0
77
77
6
0
0
89
0
0
0
71
% K
% Leu:
6
0
0
0
6
0
0
6
0
0
0
0
65
6
6
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
6
0
0
0
0
0
0
0
12
6
6
0
0
0
% N
% Pro:
0
6
0
18
0
0
0
0
0
0
6
0
0
0
0
% P
% Gln:
0
6
0
0
0
0
6
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% R
% Ser:
48
0
0
0
77
12
0
0
0
83
0
6
0
6
6
% S
% Thr:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
18
0
6
0
0
83
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _