KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF5
All Species:
48.48
Human Site:
T107
Identified Species:
66.67
UniProt:
P55010
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55010
NP_001960.2
431
49223
T107
P
E
C
E
N
P
E
T
D
L
H
V
N
P
K
Chimpanzee
Pan troglodytes
XP_001135628
431
49234
T107
P
E
C
E
N
P
E
T
D
L
H
V
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001086107
510
58170
T186
P
E
C
E
N
P
E
T
D
L
H
V
N
P
K
Dog
Lupus familis
XP_854659
425
48689
T107
P
E
C
E
N
P
E
T
E
L
H
V
N
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P59325
429
48950
T107
P
E
C
E
N
P
E
T
D
L
H
V
N
P
K
Rat
Rattus norvegicus
Q07205
429
48936
T107
P
E
C
E
N
P
E
T
D
L
H
V
N
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507766
428
48873
T107
P
E
C
E
N
P
E
T
D
L
H
V
N
P
K
Chicken
Gallus gallus
NP_001006488
430
49060
T107
P
E
C
E
N
P
E
T
D
L
H
V
N
P
K
Frog
Xenopus laevis
NP_001080311
434
49605
T107
P
E
C
D
N
P
E
T
D
L
H
V
N
P
K
Zebra Danio
Brachydanio rerio
NP_955885
429
49090
T107
P
E
C
D
N
P
E
T
D
L
H
I
N
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXK6
464
51681
T108
P
E
C
D
N
P
E
T
N
L
T
V
S
A
K
Honey Bee
Apis mellifera
XP_392511
454
50921
T108
P
A
C
D
N
P
E
T
E
L
M
V
S
S
K
Nematode Worm
Caenorhab. elegans
Q22918
436
48768
P105
L
C
K
S
C
E
N
P
E
T
Q
L
F
V
R
Sea Urchin
Strong. purpuratus
XP_787853
423
47400
L98
I
F
I
K
K
Y
V
L
C
P
E
C
D
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P55876
451
48894
E108
C
Y
G
C
G
N
P
E
T
E
I
L
I
S
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8F1
439
48604
E108
C
Y
G
C
G
N
P
E
T
E
I
L
I
T
K
Baker's Yeast
Sacchar. cerevisiae
P38431
405
45243
E106
C
G
S
C
K
N
P
E
T
E
I
I
I
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
75.8
93
N.A.
97.2
96.9
N.A.
94.9
92.8
83.4
76
N.A.
50.2
53.2
49.3
52.4
Protein Similarity:
100
99.7
80.1
95.1
N.A.
98.3
98.3
N.A.
97.6
96.7
91.9
89.5
N.A.
68
70.9
65.3
71.2
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
66.6
60
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
80
20
13.3
Percent
Protein Identity:
N.A.
30.3
N.A.
28.7
35.2
N.A.
Protein Similarity:
N.A.
46.7
N.A.
47.3
53.1
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% A
% Cys:
18
6
71
18
6
0
0
0
6
0
0
6
0
0
0
% C
% Asp:
0
0
0
24
0
0
0
0
53
0
0
0
6
0
0
% D
% Glu:
0
65
0
48
0
6
71
18
18
18
6
0
0
0
0
% E
% Phe:
0
6
0
0
0
0
0
0
0
0
0
0
6
0
0
% F
% Gly:
0
6
12
0
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% H
% Ile:
6
0
6
0
0
0
0
0
0
0
18
12
18
0
0
% I
% Lys:
0
0
6
6
12
0
0
0
0
0
0
0
0
0
89
% K
% Leu:
6
0
0
0
0
0
0
6
0
71
0
18
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
0
0
71
18
6
0
6
0
0
0
59
6
0
% N
% Pro:
71
0
0
0
0
71
18
6
0
6
0
0
0
59
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% R
% Ser:
0
0
6
6
0
0
0
0
0
0
0
0
12
12
0
% S
% Thr:
0
0
0
0
0
0
0
71
18
6
6
0
0
12
0
% T
% Val:
0
0
0
0
0
0
6
0
0
0
0
65
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
6
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _