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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARSF
All Species:
14.55
Human Site:
S273
Identified Species:
35.56
UniProt:
P54793
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54793
NP_004033.2
590
65940
S273
I
M
V
K
E
A
I
S
F
L
E
R
H
S
K
Chimpanzee
Pan troglodytes
XP_001165439
500
56448
I235
M
D
S
M
V
G
K
I
L
D
A
I
D
D
F
Rhesus Macaque
Macaca mulatta
XP_001086304
590
66040
S273
I
M
V
K
E
A
I
S
F
L
E
R
H
R
K
Dog
Lupus familis
XP_852349
704
79322
S393
I
M
V
K
E
A
I
S
F
M
E
R
N
R
E
Cat
Felis silvestris
Mouse
Mus musculus
P50427
624
66572
L278
R
L
A
D
E
A
A
L
F
L
R
R
N
R
A
Rat
Rattus norvegicus
P15589
577
62660
D269
R
L
A
S
E
A
G
D
F
L
R
R
N
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514413
576
63289
S264
L
M
L
K
E
A
I
S
F
I
Q
R
N
R
K
Chicken
Gallus gallus
Q5ZK90
535
61383
G266
S
Y
T
K
N
C
T
G
E
F
T
K
Q
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
S252
M
H
P
V
D
Y
Y
S
T
V
T
K
N
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P50473
567
62459
G251
L
L
R
D
D
T
V
G
F
I
E
D
N
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.1
94.5
63.3
N.A.
44.7
48.9
N.A.
60
21.3
N.A.
22
N.A.
N.A.
N.A.
N.A.
26.9
Protein Similarity:
100
80.8
96.7
72.1
N.A.
58
61.5
N.A.
74.4
37.9
N.A.
37.9
N.A.
N.A.
N.A.
N.A.
41.8
P-Site Identity:
100
0
93.3
73.3
N.A.
33.3
33.3
N.A.
60
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
46.6
46.6
N.A.
93.3
13.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
60
10
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
0
20
20
0
0
10
0
10
0
10
10
10
10
% D
% Glu:
0
0
0
0
60
0
0
0
10
0
40
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
70
10
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
10
10
20
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
20
0
0
% H
% Ile:
30
0
0
0
0
0
40
10
0
20
0
10
0
0
0
% I
% Lys:
0
0
0
50
0
0
10
0
0
0
0
20
0
0
30
% K
% Leu:
20
30
10
0
0
0
0
10
10
40
0
0
0
0
0
% L
% Met:
20
40
0
10
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
60
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
20
0
10
0
0
0
0
0
0
0
20
60
0
50
0
% R
% Ser:
10
0
10
10
0
0
0
50
0
0
0
0
0
10
10
% S
% Thr:
0
0
10
0
0
10
10
0
10
0
20
0
0
0
0
% T
% Val:
0
0
30
10
10
0
10
0
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _