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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
8.79
Human Site:
T597
Identified Species:
19.33
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
T597
I
C
Q
K
L
V
N
T
Q
D
M
S
A
S
Q
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
T597
I
C
Q
K
L
V
N
T
Q
D
V
S
A
S
Q
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
S255
S
I
K
E
N
I
G
S
V
F
G
Q
K
Q
V
Dog
Lupus familis
XP_536879
876
97273
T611
A
H
P
G
L
V
K
T
R
N
T
P
A
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
S598
L
P
G
P
Q
S
T
S
A
A
E
V
D
V
A
Rat
Rattus norvegicus
P97679
757
84522
E525
R
G
H
E
T
L
R
E
M
L
R
N
H
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
K595
T
P
N
V
K
R
A
K
S
E
K
K
V
A
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
R585
C
L
V
D
F
K
S
R
N
A
S
L
K
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
L577
R
R
E
V
T
V
P
L
S
L
A
G
L
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
F633
F
S
T
L
E
F
S
F
Q
N
L
R
T
R
R
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
R586
R
T
P
L
K
N
S
R
K
S
I
S
K
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
93.3
0
40
N.A.
0
0
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
53.3
N.A.
13.3
26.6
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
10
19
10
0
28
10
10
% A
% Cys:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
19
0
0
10
10
10
% D
% Glu:
0
0
10
19
10
0
0
10
0
10
10
0
0
0
0
% E
% Phe:
10
0
0
0
10
10
0
10
0
10
0
0
0
10
10
% F
% Gly:
0
10
10
10
0
0
10
0
0
0
10
10
0
0
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
19
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
19
19
10
10
10
10
0
10
10
28
0
0
% K
% Leu:
10
10
0
19
28
10
0
10
0
19
10
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
10
10
19
0
10
19
0
10
0
0
10
% N
% Pro:
0
19
19
10
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
19
0
10
0
0
0
28
0
0
10
0
10
28
% Q
% Arg:
28
10
0
0
0
10
10
19
10
0
10
10
0
19
19
% R
% Ser:
10
10
0
0
0
10
28
19
19
10
10
28
0
28
0
% S
% Thr:
10
10
10
0
19
0
10
28
0
0
10
0
10
10
0
% T
% Val:
0
0
10
19
0
37
0
0
10
0
10
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _