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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
9.09
Human Site:
T558
Identified Species:
20
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
T558
C
H
S
N
Q
E
D
T
G
C
K
F
R
V
L
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
T558
C
H
S
N
Q
E
D
T
G
C
K
F
R
V
L
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
A216
K
M
V
Q
V
L
Q
A
Y
C
I
I
S
A
G
Dog
Lupus familis
XP_536879
876
97273
S572
G
Q
L
D
H
E
N
S
G
Q
T
C
R
I
S
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
Q559
K
P
E
D
H
G
Y
Q
C
K
A
L
P
L
A
Rat
Rattus norvegicus
P97679
757
84522
N486
S
D
V
E
M
M
E
N
D
S
R
K
E
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
E556
G
V
C
E
K
S
S
E
T
L
L
P
L
S
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
T546
E
N
L
W
S
Y
E
T
L
P
E
T
K
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
T538
H
R
L
H
C
T
S
T
D
V
G
S
A
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
E594
T
L
T
K
G
D
V
E
R
V
S
E
D
N
P
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
C547
C
H
E
H
T
N
D
C
C
H
Q
E
R
R
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
100
6.6
20
N.A.
0
0
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
46.6
N.A.
13.3
20
N.A.
6.6
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
10
0
10
10
10
% A
% Cys:
28
0
10
0
10
0
0
10
19
28
0
10
0
0
0
% C
% Asp:
0
10
0
19
0
10
28
0
19
0
0
0
10
0
0
% D
% Glu:
10
0
19
19
0
28
19
19
0
0
10
19
10
0
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% F
% Gly:
19
0
0
0
10
10
0
0
28
0
10
0
0
0
19
% G
% His:
10
28
0
19
19
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
0
19
0
% I
% Lys:
19
0
0
10
10
0
0
0
0
10
19
10
10
0
0
% K
% Leu:
0
10
28
0
0
10
0
0
10
10
10
10
10
10
19
% L
% Met:
0
10
0
0
10
10
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
19
0
10
10
10
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
0
10
10
0
10
% P
% Gln:
0
10
0
10
19
0
10
10
0
10
10
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
10
0
10
0
37
10
0
% R
% Ser:
10
0
19
0
10
10
19
10
0
10
10
10
10
19
10
% S
% Thr:
10
0
10
0
10
10
0
37
10
0
10
10
0
0
10
% T
% Val:
0
10
19
0
10
0
10
0
0
19
0
0
0
19
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _