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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
5.76
Human Site:
S601
Identified Species:
12.67
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
S601
L
V
N
T
Q
D
M
S
A
S
Q
V
D
V
A
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
S601
L
V
N
T
Q
D
V
S
A
S
Q
V
D
V
A
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
Q259
N
I
G
S
V
F
G
Q
K
Q
V
Q
S
L
I
Dog
Lupus familis
XP_536879
876
97273
P615
L
V
K
T
R
N
T
P
A
S
Q
V
D
V
A
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
V602
Q
S
T
S
A
A
E
V
D
V
A
I
K
M
N
Rat
Rattus norvegicus
P97679
757
84522
N529
T
L
R
E
M
L
R
N
H
T
F
V
G
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
K599
K
R
A
K
S
E
K
K
V
A
L
S
S
E
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
L589
F
K
S
R
N
A
S
L
K
F
D
A
P
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
G581
T
V
P
L
S
L
A
G
L
R
R
A
R
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
R637
E
F
S
F
Q
N
L
R
T
R
R
L
E
R
L
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
S590
K
N
S
R
K
S
I
S
K
D
N
Y
R
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
93.3
0
66.6
N.A.
0
6.6
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
80
N.A.
20
26.6
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
19
10
0
28
10
10
19
0
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
19
0
0
10
10
10
0
28
0
0
% D
% Glu:
10
0
0
10
0
10
10
0
0
0
0
0
10
19
0
% E
% Phe:
10
10
0
10
0
10
0
0
0
10
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
10
% I
% Lys:
19
10
10
10
10
0
10
10
28
0
0
0
10
0
0
% K
% Leu:
28
10
0
10
0
19
10
10
10
0
10
10
0
10
19
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
0
% M
% Asn:
10
10
19
0
10
19
0
10
0
0
10
0
0
0
19
% N
% Pro:
0
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
28
0
0
10
0
10
28
10
0
0
10
% Q
% Arg:
0
10
10
19
10
0
10
10
0
19
19
0
19
10
0
% R
% Ser:
0
10
28
19
19
10
10
28
0
28
0
10
19
10
0
% S
% Thr:
19
0
10
28
0
0
10
0
10
10
0
0
0
0
0
% T
% Val:
0
37
0
0
10
0
10
10
10
10
10
37
0
37
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _