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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
5.76
Human Site:
S547
Identified Species:
12.67
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
S547
P
E
T
D
D
S
F
S
D
V
D
C
H
S
N
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
S547
P
E
T
D
D
C
F
S
D
V
D
C
H
S
N
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
K205
E
F
Q
R
N
I
K
K
E
Y
A
K
M
V
Q
Dog
Lupus familis
XP_536879
876
97273
A561
P
E
I
D
H
H
P
A
D
A
G
G
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
G548
D
C
R
P
P
G
T
G
Q
S
L
K
P
E
D
Rat
Rattus norvegicus
P97679
757
84522
H475
P
G
S
S
R
K
R
H
P
E
D
S
D
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
L545
K
S
H
P
R
N
C
L
E
T
I
G
V
C
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
K535
V
K
A
E
I
V
D
K
P
M
D
E
N
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
E527
S
S
Q
E
P
S
Q
E
T
P
E
H
R
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
T583
P
I
R
F
E
E
P
T
S
D
N
T
L
T
K
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
V536
Q
A
D
G
L
V
F
V
D
N
E
C
H
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
93.3
0
26.6
N.A.
0
13.3
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
13.3
40
N.A.
6.6
20
N.A.
13.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
10
0
10
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
10
10
0
0
0
0
28
0
10
0
% C
% Asp:
10
0
10
28
19
0
10
0
37
10
37
0
10
0
19
% D
% Glu:
10
28
0
19
10
10
0
10
19
10
19
10
0
19
19
% E
% Phe:
0
10
0
10
0
0
28
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
10
0
10
0
0
10
19
0
0
0
% G
% His:
0
0
10
0
10
10
0
10
0
0
0
10
28
0
19
% H
% Ile:
0
10
10
0
10
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
10
10
0
0
0
10
10
19
0
0
0
19
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
10
0
0
10
0
10
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
10
10
0
10
0
19
% N
% Pro:
46
0
0
19
19
0
19
0
19
10
0
0
10
0
0
% P
% Gln:
10
0
19
0
0
0
10
0
10
0
0
0
10
0
10
% Q
% Arg:
0
0
19
10
19
0
10
0
0
0
0
0
10
0
0
% R
% Ser:
10
19
10
10
0
19
0
19
10
10
0
10
0
19
0
% S
% Thr:
0
0
19
0
0
0
10
10
10
10
0
10
0
10
0
% T
% Val:
10
0
0
0
0
19
0
10
0
19
0
0
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _