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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
10.3
Human Site:
S457
Identified Species:
22.67
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
S457
K
R
G
M
L
S
S
S
T
S
G
A
I
S
D
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
S457
K
R
G
M
L
S
S
S
T
S
D
A
I
S
D
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
T115
G
L
T
L
K
H
H
T
S
K
I
Q
E
F
A
Dog
Lupus familis
XP_536879
876
97273
H471
I
Q
L
P
G
A
L
H
S
P
C
T
P
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
Y458
K
R
G
V
L
S
S
Y
P
S
D
V
I
S
Y
Rat
Rattus norvegicus
P97679
757
84522
R385
V
H
A
Y
Q
M
V
R
T
D
S
R
D
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
T455
R
K
L
S
F
S
S
T
S
D
T
L
N
S
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
M445
A
G
P
S
Q
K
K
M
L
S
F
V
S
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
R437
C
F
R
P
S
S
Q
R
E
A
K
R
A
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
N493
M
G
K
R
K
H
E
N
I
S
T
I
L
S
E
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
E446
V
T
D
V
I
G
S
E
C
E
V
S
V
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
93.3
0
0
N.A.
60
6.6
N.A.
20
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
20
20
N.A.
66.6
6.6
N.A.
46.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
10
0
0
0
10
0
19
10
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
19
19
0
10
10
19
% D
% Glu:
0
0
0
0
0
0
10
10
10
10
0
0
10
0
10
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
10
0
0
10
0
% F
% Gly:
10
19
28
0
10
10
0
0
0
0
10
0
0
10
0
% G
% His:
0
10
0
0
0
19
10
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
0
0
10
0
10
10
28
0
0
% I
% Lys:
28
10
10
0
19
10
10
0
0
10
10
0
0
0
10
% K
% Leu:
0
10
19
10
28
0
10
0
10
0
0
10
10
0
0
% L
% Met:
10
0
0
19
0
10
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
19
0
0
0
0
10
10
0
0
10
0
10
% P
% Gln:
0
10
0
0
19
0
10
0
0
0
0
10
0
10
10
% Q
% Arg:
10
28
10
10
0
0
0
19
0
0
0
19
0
10
0
% R
% Ser:
0
0
0
19
10
46
46
19
28
46
10
10
10
46
19
% S
% Thr:
0
10
10
0
0
0
0
19
28
0
19
10
0
0
10
% T
% Val:
19
0
0
19
0
0
10
0
0
0
10
19
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _