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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
5.76
Human Site:
S405
Identified Species:
12.67
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
S405
E
K
Q
D
Q
S
P
S
L
R
T
G
E
E
K
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
S405
E
K
Q
D
Q
S
P
S
L
R
T
G
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
S63
G
Q
V
V
L
S
L
S
T
A
V
K
E
L
V
Dog
Lupus familis
XP_536879
876
97273
E419
S
P
A
L
F
R
T
E
G
E
E
K
R
A
V
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
L406
K
Q
D
N
S
P
S
L
K
S
T
A
D
E
K
Rat
Rattus norvegicus
P97679
757
84522
K333
V
Q
Q
H
I
E
S
K
L
L
G
S
N
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
P403
P
A
L
E
E
W
S
P
R
T
K
G
E
E
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
G393
C
S
D
D
Q
E
M
G
S
V
S
E
T
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
R385
A
L
S
N
M
F
S
R
S
P
S
S
S
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
D441
E
G
S
L
S
V
H
D
V
T
H
L
D
K
T
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
D394
R
S
T
T
H
E
S
D
N
E
N
Y
H
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
100
20
0
N.A.
20
13.3
N.A.
26.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
0
N.A.
46.6
20
N.A.
40
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
0
0
0
10
0
10
0
10
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
28
0
0
0
19
0
0
0
0
19
0
0
% D
% Glu:
28
0
0
10
10
28
0
10
0
19
10
10
37
37
0
% E
% Phe:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
10
10
0
10
28
0
0
10
% G
% His:
0
0
0
10
10
0
10
0
0
0
10
0
10
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
19
0
0
0
0
0
10
10
0
10
19
0
10
37
% K
% Leu:
0
10
10
19
10
0
10
10
28
10
0
10
0
19
0
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
0
0
0
10
0
10
0
10
0
0
% N
% Pro:
10
10
0
0
0
10
19
10
0
10
0
0
0
0
0
% P
% Gln:
0
28
28
0
28
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
0
0
0
10
0
10
10
19
0
0
10
0
0
% R
% Ser:
10
19
19
0
19
28
46
28
19
10
19
19
10
10
10
% S
% Thr:
0
0
10
10
0
0
10
0
10
19
28
0
10
10
19
% T
% Val:
10
0
10
10
0
10
0
0
10
10
10
0
0
0
19
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _