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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS2
All Species:
8.79
Human Site:
S373
Identified Species:
19.33
UniProt:
P54278
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54278
NP_000526.1
862
95798
S373
D
V
N
K
L
N
V
S
Q
Q
P
L
L
D
V
Chimpanzee
Pan troglodytes
XP_001141671
862
95782
S373
D
V
N
K
L
N
V
S
Q
Q
P
L
L
D
V
Rhesus Macaque
Macaca mulatta
XP_001109243
487
53942
D46
A
K
A
I
K
P
I
D
R
K
S
V
H
Q
I
Dog
Lupus familis
XP_536879
876
97273
S383
N
V
N
K
L
T
V
S
Q
Q
P
L
L
D
I
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
N373
D
A
N
K
L
N
V
N
Q
Q
P
L
L
D
V
Rat
Rattus norvegicus
P97679
757
84522
F316
P
T
K
H
E
V
H
F
L
H
E
E
S
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512507
879
98519
N375
D
V
N
K
L
N
I
N
Q
K
L
L
L
D
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693648
849
94707
N370
G
V
N
K
I
S
L
N
H
I
S
P
A
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786592
816
90290
N365
R
S
S
C
Y
D
V
N
Q
K
P
L
S
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567236
923
102666
M418
E
I
D
N
S
S
P
M
E
K
F
K
F
E
I
Baker's Yeast
Sacchar. cerevisiae
P14242
873
99337
R366
Q
E
L
A
L
P
K
R
M
C
S
Q
S
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
50.4
77
N.A.
73.4
22.9
N.A.
70
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
50.1
Protein Similarity:
100
99
52.5
83.9
N.A.
81.3
41.5
N.A.
82.2
N.A.
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
67.1
P-Site Identity:
100
100
0
80
N.A.
86.6
0
N.A.
73.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
93.3
6.6
N.A.
93.3
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.3
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.6
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
0
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
37
0
10
0
0
10
0
10
0
0
0
0
0
46
0
% D
% Glu:
10
10
0
0
10
0
0
0
10
0
10
10
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
10
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
10
0
10
10
0
0
10
0
0
% H
% Ile:
0
10
0
10
10
0
19
0
0
10
0
0
0
10
28
% I
% Lys:
0
10
10
55
10
0
10
0
0
37
0
10
0
0
0
% K
% Leu:
0
0
10
0
55
0
10
0
10
0
10
55
46
0
10
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
10
0
55
10
0
37
0
37
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
19
10
0
0
0
46
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
55
37
0
10
0
10
10
% Q
% Arg:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
10
19
0
28
0
0
28
0
28
0
0
% S
% Thr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
0
46
0
0
0
10
46
0
0
0
0
10
0
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _