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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
10.61
Human Site:
S507
Identified Species:
21.21
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S507
R
G
N
I
L
K
N
S
V
G
E
N
I
E
P
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S636
R
G
N
I
L
K
N
S
V
G
E
N
I
E
P
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
V462
K
T
C
F
V
G
S
V
K
H
T
Q
S
E
N
Dog
Lupus familis
XP_536002
930
105612
S507
K
G
N
T
L
K
N
S
M
G
E
N
I
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
M486
T
D
S
P
G
D
C
M
D
R
E
K
I
E
K
Rat
Rattus norvegicus
NP_001009535
919
103710
I507
E
N
I
E
P
V
K
I
L
V
P
Q
K
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
P498
C
L
P
G
D
S
L
P
S
H
T
L
P
G
I
Chicken
Gallus gallus
NP_001006508
916
103017
N503
F
K
N
S
S
G
D
N
L
E
P
V
K
V
L
Frog
Xenopus laevis
NP_001079545
925
103654
L507
K
D
S
L
G
D
N
L
E
P
V
K
L
L
N
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
S498
T
E
A
K
S
V
K
S
S
P
S
K
K
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
S365
F
N
D
S
E
G
I
S
M
I
C
D
I
L
E
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
R509
L
S
E
V
P
V
L
R
N
Q
T
S
E
C
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
6.6
80
N.A.
20
0
N.A.
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
26.6
93.3
N.A.
26.6
6.6
N.A.
0
26.6
33.3
6.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
9
0
9
0
0
0
9
0
0
0
9
0
0
9
0
% C
% Asp:
0
17
9
0
9
17
9
0
9
0
0
9
0
0
0
% D
% Glu:
9
9
9
9
9
0
0
0
9
9
34
0
9
42
9
% E
% Phe:
17
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
25
0
9
17
25
0
0
0
25
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
9
17
0
0
9
9
0
9
0
0
42
0
9
% I
% Lys:
25
9
0
9
0
25
17
0
9
0
0
25
25
0
9
% K
% Leu:
9
9
0
9
25
0
17
9
17
0
0
9
9
17
17
% L
% Met:
0
0
0
0
0
0
0
9
17
0
0
0
0
0
0
% M
% Asn:
0
17
34
0
0
0
34
9
9
0
0
25
0
0
17
% N
% Pro:
0
0
9
9
17
0
0
9
0
17
17
0
9
9
25
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
17
0
0
9
% Q
% Arg:
17
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% R
% Ser:
0
9
17
17
17
9
9
42
17
0
9
9
9
9
9
% S
% Thr:
17
9
0
9
0
0
0
0
0
0
25
0
0
0
0
% T
% Val:
0
0
0
9
9
25
0
9
17
9
9
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _