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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
6.36
Human Site:
S478
Identified Species:
12.73
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S478
N
K
D
H
I
D
E
S
G
E
N
E
E
E
A
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S607
N
K
D
H
I
D
E
S
G
E
N
E
E
E
A
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
K433
S
N
T
D
K
N
T
K
N
A
F
Q
D
I
S
Dog
Lupus familis
XP_536002
930
105612
N478
N
K
S
N
R
D
E
N
R
K
N
E
E
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
S457
E
K
R
G
V
L
S
S
Y
P
S
D
V
I
S
Rat
Rattus norvegicus
NP_001009535
919
103710
P478
E
D
G
K
K
T
L
P
E
K
A
L
E
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
D469
P
L
H
S
A
P
P
D
D
P
L
P
G
S
I
Chicken
Gallus gallus
NP_001006508
916
103017
E474
L
L
S
S
D
N
A
E
E
A
L
V
P
E
D
Frog
Xenopus laevis
NP_001079545
925
103654
K478
V
S
E
K
D
T
F
K
K
T
T
L
I
N
V
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
I469
G
R
V
F
S
N
Q
I
T
G
E
Y
L
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
G336
D
V
D
L
K
Q
A
G
Q
E
S
T
L
A
S
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
F480
S
N
G
P
S
G
S
F
Q
S
K
L
S
N
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
0
53.3
N.A.
13.3
6.6
N.A.
0
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
33.3
73.3
N.A.
40
13.3
N.A.
0
13.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
17
0
0
17
9
0
0
9
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
9
25
9
17
25
0
9
9
0
0
9
9
0
9
% D
% Glu:
17
0
9
0
0
0
25
9
17
25
9
25
34
34
0
% E
% Phe:
0
0
0
9
0
0
9
9
0
0
9
0
0
0
9
% F
% Gly:
9
0
17
9
0
9
0
9
17
9
0
0
9
9
0
% G
% His:
0
0
9
17
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
0
0
9
0
0
0
0
9
25
9
% I
% Lys:
0
34
0
17
25
0
0
17
9
17
9
0
0
0
0
% K
% Leu:
9
17
0
9
0
9
9
0
0
0
17
25
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
17
0
9
0
25
0
9
9
0
25
0
0
17
0
% N
% Pro:
9
0
0
9
0
9
9
9
0
17
0
9
9
0
9
% P
% Gln:
0
0
0
0
0
9
9
0
17
0
0
9
0
0
0
% Q
% Arg:
0
9
9
0
9
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
17
9
17
17
17
0
17
25
0
9
17
0
9
9
25
% S
% Thr:
0
0
9
0
0
17
9
0
9
9
9
9
0
0
0
% T
% Val:
9
9
9
0
9
0
0
0
0
0
0
9
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _