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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
33.94
Human Site:
S475
Identified Species:
46.67
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S475
Q
L
D
T
G
D
F
S
T
A
F
F
N
S
I
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S475
Q
L
D
T
G
D
F
S
T
A
F
F
N
S
I
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S596
Q
L
D
T
G
D
F
S
T
A
F
F
N
S
I
Dog
Lupus familis
XP_543550
1017
111618
S475
Q
L
D
T
G
D
F
S
T
A
F
F
N
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S475
Q
L
D
T
G
D
F
S
T
A
F
F
N
S
I
Rat
Rattus norvegicus
NP_001129232
1015
111665
S475
Q
L
D
T
G
D
F
S
T
A
F
F
N
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T475
L
C
I
A
Q
L
D
T
G
D
F
S
T
A
F
Frog
Xenopus laevis
Q8QFR2
1013
112021
S475
Q
L
D
T
G
D
F
S
T
A
F
F
N
S
I
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
S475
Q
L
D
T
G
D
F
S
P
A
L
F
N
S
V
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
D475
I
A
Q
L
D
T
G
D
F
S
P
A
L
F
N
Fruit Fly
Dros. melanogaster
O17468
1047
113397
A472
A
L
T
S
C
S
A
A
I
G
T
L
P
A
A
Honey Bee
Apis mellifera
XP_001122939
838
91355
T321
V
V
I
H
E
L
F
T
H
S
V
L
D
A
S
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
V418
F
V
T
C
P
E
D
V
L
I
K
R
K
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
L447
P
G
L
V
V
L
S
L
E
V
P
E
V
S
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
D475
Q
K
V
Y
R
R
P
D
G
R
K
R
I
I
P
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
N323
K
V
H
H
F
D
K
N
I
D
S
V
V
A
T
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
E473
P
P
E
K
P
E
E
E
S
A
D
K
T
A
E
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
100
80
0
6.6
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
100
86.6
6.6
26.6
40
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
6.6
N.A.
6.6
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
6
0
0
6
6
0
53
0
6
0
30
6
% A
% Cys:
0
6
0
6
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
48
0
6
53
12
12
0
12
6
0
6
0
0
% D
% Glu:
0
0
6
0
6
12
6
6
6
0
0
6
0
0
6
% E
% Phe:
6
0
0
0
6
0
53
0
6
0
48
48
0
6
6
% F
% Gly:
0
6
0
0
48
0
6
0
12
6
0
0
0
0
0
% G
% His:
0
0
6
12
0
0
0
0
6
0
0
0
0
0
6
% H
% Ile:
6
0
12
0
0
0
0
0
12
6
0
0
6
6
42
% I
% Lys:
6
6
0
6
0
0
6
0
0
0
12
6
6
6
0
% K
% Leu:
6
53
6
6
0
18
0
6
6
0
6
12
6
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
0
0
0
48
0
6
% N
% Pro:
12
6
0
0
12
0
6
0
6
0
12
0
6
0
6
% P
% Gln:
53
0
6
0
6
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
6
6
0
0
0
6
0
12
0
0
0
% R
% Ser:
0
0
0
6
0
6
6
48
6
12
6
6
0
53
6
% S
% Thr:
0
0
12
48
0
6
0
12
42
0
6
0
12
0
6
% T
% Val:
6
18
6
6
6
0
0
6
0
6
6
6
12
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _