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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUB1
All Species:
25.76
Human Site:
T45
Identified Species:
40.48
UniProt:
P53999
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53999
NP_006704.3
127
14395
T45
K
K
Q
K
T
G
E
T
S
R
A
L
S
S
S
Chimpanzee
Pan troglodytes
XP_001154452
153
17638
T71
K
K
Q
K
T
G
E
T
S
R
A
L
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001089347
166
18812
T84
K
K
Q
K
T
G
E
T
S
R
A
L
S
S
S
Dog
Lupus familis
XP_536425
318
35815
T236
K
K
Q
K
T
G
E
T
S
R
A
L
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P11031
127
14409
T45
K
K
Q
K
P
G
E
T
S
R
A
L
A
S
S
Rat
Rattus norvegicus
Q63396
127
14423
S45
K
K
Q
K
P
G
E
S
S
R
A
L
A
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521441
125
14064
E43
V
K
K
Q
K
T
G
E
S
S
K
G
A
A
S
Chicken
Gallus gallus
Q5ZK63
126
14219
E44
V
K
K
Q
K
T
G
E
S
S
K
G
A
A
S
Frog
Xenopus laevis
NP_001084564
128
14361
E46
A
K
K
Q
K
T
G
E
S
S
K
G
G
A
S
Zebra Danio
Brachydanio rerio
NP_001002505
124
13869
G42
P
A
K
K
Q
K
S
G
E
S
S
K
P
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLR5
110
12170
S31
A
S
K
K
A
K
E
S
D
A
P
N
S
D
P
Honey Bee
Apis mellifera
XP_624593
119
13804
S37
E
D
K
E
E
K
V
S
K
K
L
K
S
E
S
Nematode Worm
Caenorhab. elegans
Q94045
124
14428
A44
E
K
Q
E
V
K
K
A
K
N
E
E
E
V
S
Sea Urchin
Strong. purpuratus
XP_001177085
115
13090
K36
A
A
K
P
A
A
K
K
P
V
K
K
S
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65154
107
12065
V28
T
H
A
P
A
K
K
V
A
K
P
A
D
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83
67.4
39.6
N.A.
93.6
93.6
N.A.
91.3
89.7
79.6
70.8
N.A.
32.2
41.7
33
39.3
Protein Similarity:
100
83
72.2
39.6
N.A.
96
96.8
N.A.
93.6
94.4
91.4
85
N.A.
51.9
62.9
51.9
59
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
20
20
20
13.3
N.A.
20
13.3
20
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
46.6
46.6
40
26.6
N.A.
33.3
46.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
14
7
0
20
7
0
7
7
7
40
7
27
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
7
0
0
0
7
14
7
% D
% Glu:
14
0
0
14
7
0
47
20
7
0
7
7
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
40
20
7
0
0
0
20
7
0
7
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
40
67
47
54
20
34
20
7
14
14
27
20
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
7
40
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
7
0
0
14
14
0
0
0
7
0
14
0
7
0
7
% P
% Gln:
0
0
47
20
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
7
20
60
27
7
0
47
54
80
% S
% Thr:
7
0
0
0
27
20
0
34
0
0
0
0
0
0
0
% T
% Val:
14
0
0
0
7
0
7
7
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _