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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMTN All Species: 11.21
Human Site: T481 Identified Species: 35.24
UniProt: P53814 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53814 NP_008863.3 917 99520 T481 T G R V L L P T G N Q R A E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094503 461 49839 T99 P A P G T P C T P S P P P A P
Dog Lupus familis XP_534737 915 98990 T480 T S R V L L P T G N Q R A E L
Cat Felis silvestris
Mouse Mus musculus Q921U8 923 100270 T479 T G R V L L P T G N Q R A E L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507534 1002 108621 S577 G E R G P C P S S E E P S S L
Chicken Gallus gallus
Frog Xenopus laevis NP_001089402 873 96406 P446 S S R V V G Q P G N Q R A E L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres Q2KN94 1118 123301 Q654 A Q R Q L S E Q E R A L E K Q
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797893 1158 125082 I725 S S R Y G G S I S E E S S L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 27.9 86.8 N.A. 79.8 N.A. N.A. 45.5 N.A. 39.1 N.A. 20 N.A. N.A. N.A. 25
Protein Similarity: 100 N.A. 37.7 90.6 N.A. 85.1 N.A. N.A. 55.8 N.A. 54.2 N.A. 38 N.A. N.A. N.A. 40.9
P-Site Identity: 100 N.A. 6.6 93.3 N.A. 100 N.A. N.A. 20 N.A. 60 N.A. 13.3 N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 13.3 93.3 N.A. 100 N.A. N.A. 40 N.A. 73.3 N.A. 20 N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 0 0 0 0 0 0 0 0 13 0 50 13 0 % A
% Cys: 0 0 0 0 0 13 13 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 13 0 0 0 0 13 0 13 25 25 0 13 50 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 25 0 25 13 25 0 0 50 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 0 0 0 0 50 38 0 0 0 0 0 13 0 13 63 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 13 % N
% Pro: 13 0 13 0 13 13 50 13 13 0 13 25 13 0 13 % P
% Gln: 0 13 0 13 0 0 13 13 0 0 50 0 0 0 13 % Q
% Arg: 0 0 88 0 0 0 0 0 0 13 0 50 0 0 0 % R
% Ser: 25 38 0 0 0 13 13 13 25 13 0 13 25 13 0 % S
% Thr: 38 0 0 0 13 0 0 50 0 0 0 0 0 0 0 % T
% Val: 0 0 0 50 13 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _