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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC5A3 All Species: 18.18
Human Site: S673 Identified Species: 40
UniProt: P53794 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53794 NP_008864.3 718 79694 S673 S K S L S K R S L R D L M E E
Chimpanzee Pan troglodytes XP_531445 805 89489 S673 S K S L S K R S L R D L M E E
Rhesus Macaque Macaca mulatta XP_001090103 718 79480 S673 S K S L S K R S L R D L M E E
Dog Lupus familis XP_535588 718 79527 S673 S K S L S K R S L R D L M E E
Cat Felis silvestris
Mouse Mus musculus Q9JKZ2 718 79536 S673 S K S L S K R S L R D L M D E
Rat Rattus norvegicus Q9Z1F2 673 73587 P633 M E K D K E E P P S K V E P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512341 714 77297 G672 S P R G L R D G A A D G E A V
Chicken Gallus gallus XP_414862 675 74403 V634 R Q E N P E D V A P A K P E R
Frog Xenopus laevis NP_001079025 673 74118 P633 G D K H D Q A P P A P L E P A
Zebra Danio Brachydanio rerio A8WHP3 657 72206 E617 K Q D L T E E E R Q A L E K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797570 671 73834 D628 F L G Y N P K D D H E V P D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.8 97.3 96.6 N.A. 93.4 46.3 N.A. 81.7 46.5 46.9 44.9 N.A. N.A. N.A. N.A. 45.8
Protein Similarity: 100 88.3 98.1 98.6 N.A. 97 64 N.A. 89.2 66.1 66.7 63.9 N.A. N.A. N.A. N.A. 63.9
P-Site Identity: 100 100 100 100 N.A. 93.3 0 N.A. 13.3 6.6 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 20 20 13.3 53.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 19 19 19 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 10 10 0 19 10 10 0 55 0 0 19 0 % D
% Glu: 0 10 10 0 0 28 19 10 0 0 10 0 37 46 55 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 10 0 0 0 10 0 0 0 10 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 46 19 0 10 46 10 0 0 0 10 10 0 10 10 % K
% Leu: 0 10 0 55 10 0 0 0 46 0 0 64 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 46 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 10 10 0 19 19 10 10 0 19 19 0 % P
% Gln: 0 19 0 0 0 10 0 0 0 10 0 0 0 0 0 % Q
% Arg: 10 0 10 0 0 10 46 0 10 46 0 0 0 0 10 % R
% Ser: 55 0 46 0 46 0 0 46 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 19 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _