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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC5A3 All Species: 20.3
Human Site: S559 Identified Species: 44.67
UniProt: P53794 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53794 NP_008864.3 718 79694 S559 L V V K E N C S P K E E P Y Q
Chimpanzee Pan troglodytes XP_531445 805 89489 S559 L V V K E N C S P K E E P Y K
Rhesus Macaque Macaca mulatta XP_001090103 718 79480 S559 L V V K E S C S P K E E P Y K
Dog Lupus familis XP_535588 718 79527 S559 L V V K E S C S P K D E P Y K
Cat Felis silvestris
Mouse Mus musculus Q9JKZ2 718 79536 S559 L V T K E S C S Q K D E P Y K
Rat Rattus norvegicus Q9Z1F2 673 73587 H520 P A V V K D V H Y L Y F S M I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512341 714 77297 G559 P A A A P G G G G H K G D P Y
Chicken Gallus gallus XP_414862 675 74403 L521 V L R Y M H Y L Y F S M V L A
Frog Xenopus laevis NP_001079025 673 74118 Y520 G V V K Y V H Y L Y L S M I L
Zebra Danio Brachydanio rerio A8WHP3 657 72206 S504 E F V Y G T P S C G E T D L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797570 671 73834 T515 L Y Y N C I V T L V S L V V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.8 97.3 96.6 N.A. 93.4 46.3 N.A. 81.7 46.5 46.9 44.9 N.A. N.A. N.A. N.A. 45.8
Protein Similarity: 100 88.3 98.1 98.6 N.A. 97 64 N.A. 89.2 66.1 66.7 63.9 N.A. N.A. N.A. N.A. 63.9
P-Site Identity: 100 93.3 86.6 80 N.A. 66.6 6.6 N.A. 0 0 20 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 20 N.A. 6.6 20 20 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 10 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 46 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 19 0 19 0 0 % D
% Glu: 10 0 0 0 46 0 0 0 0 0 37 46 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 0 10 0 0 0 % F
% Gly: 10 0 0 0 10 10 10 10 10 10 0 10 0 0 0 % G
% His: 0 0 0 0 0 10 10 10 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 0 55 10 0 0 0 0 46 10 0 0 0 37 % K
% Leu: 55 10 0 0 0 0 0 10 19 10 10 10 0 19 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 10 10 10 0 % M
% Asn: 0 0 0 10 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 0 0 0 10 0 10 0 37 0 0 0 46 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 28 0 55 0 0 19 10 10 0 0 % S
% Thr: 0 0 10 0 0 10 0 10 0 0 0 10 0 0 10 % T
% Val: 10 55 64 10 0 10 19 0 0 10 0 0 19 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 19 10 0 10 10 19 10 10 0 0 46 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _