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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
56.36
Human Site:
Y204
Identified Species:
82.67
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
Y204
R
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
Y205
R
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
Y204
R
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Dog
Lupus familis
XP_537950
272
31050
Y208
R
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
Y208
R
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Rat
Rattus norvegicus
XP_228867
274
31111
Y210
R
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
Y208
K
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Chicken
Gallus gallus
Q5F339
273
31420
Y209
R
I
R
S
W
M
G
Y
E
L
P
F
D
R
H
Frog
Xenopus laevis
NP_001087149
267
30990
Y203
R
M
R
S
W
M
G
Y
E
L
P
F
D
R
H
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
Y205
R
I
R
H
W
M
G
Y
E
L
P
F
D
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
Y198
R
F
R
S
W
L
G
Y
E
L
P
F
D
R
H
Honey Bee
Apis mellifera
XP_392497
276
32212
Y195
R
I
R
Y
W
M
G
Y
E
L
P
F
D
R
H
Nematode Worm
Caenorhab. elegans
P53703
280
31245
Y193
F
R
N
L
F
L
G
Y
D
L
P
F
D
R
H
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
Y226
K
I
R
C
W
M
G
Y
E
K
P
F
D
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
Q186
L
F
P
S
H
F
S
Q
E
L
P
F
D
R
H
Red Bread Mold
Neurospora crassa
P14187
346
38128
R258
A
L
L
Q
V
L
G
R
I
N
S
K
Y
A
T
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
93.3
93.3
N.A.
86.6
93.3
53.3
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
93.3
93.3
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
0
0
94
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
88
0
0
0
0
0
0
% E
% Phe:
7
13
0
0
7
7
0
0
0
0
0
94
0
0
0
% F
% Gly:
0
0
0
0
0
0
94
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
94
% H
% Ile:
0
69
0
0
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% K
% Leu:
7
7
7
7
0
19
0
0
0
88
0
0
0
0
0
% L
% Met:
0
7
0
0
0
75
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
94
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
69
7
82
0
0
0
0
7
0
0
0
0
0
94
0
% R
% Ser:
0
0
0
69
0
0
7
0
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
82
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
88
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _