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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
55.15
Human Site:
S193
Identified Species:
80.89
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
S193
G
G
K
A
K
E
Y
S
P
R
A
R
I
R
S
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
S194
G
G
K
A
K
E
Y
S
P
R
A
R
I
R
S
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
S193
G
G
K
A
K
E
Y
S
P
R
A
R
I
R
S
Dog
Lupus familis
XP_537950
272
31050
S197
G
G
K
A
K
E
Y
S
P
R
A
R
I
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
S197
G
G
K
A
R
E
Y
S
P
R
A
R
I
R
S
Rat
Rattus norvegicus
XP_228867
274
31111
S199
G
G
K
A
R
E
Y
S
P
R
A
R
I
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
S197
G
G
K
A
K
D
Y
S
P
R
A
K
I
R
S
Chicken
Gallus gallus
Q5F339
273
31420
S198
G
G
K
A
K
E
Y
S
P
R
A
R
I
R
S
Frog
Xenopus laevis
NP_001087149
267
30990
S192
G
G
K
A
K
E
Y
S
P
R
A
R
M
R
S
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
S194
G
G
K
A
K
E
F
S
P
R
A
R
I
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
S187
G
G
K
A
K
D
F
S
P
R
A
R
F
R
S
Honey Bee
Apis mellifera
XP_392497
276
32212
S184
G
G
K
A
K
Q
Y
S
P
R
A
R
I
R
Y
Nematode Worm
Caenorhab. elegans
P53703
280
31245
P182
G
D
A
K
N
L
S
P
R
A
R
F
R
N
L
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
S215
G
G
R
Y
N
D
L
S
P
R
A
K
I
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
L175
P
R
A
R
W
M
H
L
C
G
L
L
F
P
S
Red Bread Mold
Neurospora crassa
P14187
346
38128
T247
Q
G
R
P
K
D
M
T
P
K
A
A
L
L
Q
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
100
93.3
86.6
N.A.
80
86.6
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
93.3
93.3
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
75
0
0
0
0
0
7
88
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
0
7
0
0
0
25
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
57
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
7
13
0
0
% F
% Gly:
88
88
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
69
0
0
% I
% Lys:
0
0
75
7
69
0
0
0
0
7
0
13
0
0
0
% K
% Leu:
0
0
0
0
0
7
7
7
0
0
7
7
7
7
7
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
7
0
0
7
0
0
0
7
88
0
0
0
0
7
0
% P
% Gln:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
7
13
7
13
0
0
0
7
82
7
69
7
82
0
% R
% Ser:
0
0
0
0
0
0
7
82
0
0
0
0
0
0
69
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
63
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _