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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPA
All Species:
39.7
Human Site:
S279
Identified Species:
67.18
UniProt:
P53621
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53621
NP_001091868.1
1224
138346
S279
S
I
R
V
W
D
M
S
K
R
T
G
V
Q
T
Chimpanzee
Pan troglodytes
XP_001171498
1224
138329
S279
S
I
R
V
W
D
M
S
K
R
T
G
V
Q
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536131
1241
139883
S296
S
I
R
V
W
D
M
S
K
R
T
G
V
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIE6
1224
138428
S279
S
I
R
V
W
D
M
S
K
R
T
G
V
Q
T
Rat
Rattus norvegicus
O35142
905
102533
E96
L
E
R
V
H
M
F
E
A
H
S
D
Y
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026576
1224
138533
S279
S
I
R
V
W
D
M
S
K
R
T
G
V
Q
T
Frog
Xenopus laevis
NP_001086488
1224
138559
S279
S
I
R
V
W
D
M
S
K
R
T
G
V
Q
T
Zebra Danio
Brachydanio rerio
NP_001001941
1226
138438
S280
S
I
R
V
W
D
M
S
K
R
T
G
V
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O62621
914
102694
A106
S
D
Y
L
R
C
I
A
V
H
P
T
Q
P
L
Honey Bee
Apis mellifera
XP_623198
1214
137977
S281
S
I
R
V
W
D
M
S
K
R
T
C
L
H
T
Nematode Worm
Caenorhab. elegans
Q20168
1000
111088
V191
H
E
K
G
V
N
C
V
D
Y
Y
H
G
G
E
Sea Urchin
Strong. purpuratus
XP_001179078
1211
136717
S267
S
I
R
V
W
D
M
S
K
R
T
C
I
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A40
1216
136548
T278
S
I
R
V
W
D
A
T
K
R
T
G
L
Q
T
Baker's Yeast
Sacchar. cerevisiae
P53622
1201
135589
D283
T
L
R
V
W
D
L
D
K
R
T
P
V
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
96.8
N.A.
98.5
23.1
N.A.
N.A.
96.5
93.1
86.3
N.A.
20.1
73.3
20.7
77.5
Protein Similarity:
100
99.9
N.A.
97.7
N.A.
99.1
37.8
N.A.
N.A.
98.5
97.1
94.7
N.A.
37.9
85
39
87
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
N.A.
100
100
100
N.A.
6.6
80
0
86.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
N.A.
100
100
100
N.A.
26.6
86.6
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.5
43.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.4
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
15
0
0
0
% C
% Asp:
0
8
0
0
0
79
0
8
8
0
0
8
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
58
8
8
0
% G
% His:
8
0
0
0
8
0
0
0
0
15
0
8
0
8
0
% H
% Ile:
0
72
0
0
0
0
8
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
79
0
0
0
0
8
0
% K
% Leu:
8
8
0
8
0
0
8
0
0
0
0
0
15
0
8
% L
% Met:
0
0
0
0
0
8
65
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
65
8
% Q
% Arg:
0
0
86
0
8
0
0
0
0
79
0
0
0
0
8
% R
% Ser:
79
0
0
0
0
0
0
65
0
0
8
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
79
8
0
0
72
% T
% Val:
0
0
0
86
8
0
0
8
8
0
0
0
58
0
0
% V
% Trp:
0
0
0
0
79
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _