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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPB1 All Species: 54.24
Human Site: Y379 Identified Species: 91.79
UniProt: P53618 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53618 NP_001137533.1 953 107142 Y379 E H E D T D K Y R Q L L V R T
Chimpanzee Pan troglodytes XP_001172023 953 107170 Y379 E H E D T D K Y R Q L L V R T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534069 1054 117865 Y480 E H E D T D K Y R Q L L V R T
Cat Felis silvestris
Mouse Mus musculus Q9JIF7 953 107048 Y379 E H E D T D K Y R Q L L V R T
Rat Rattus norvegicus P23514 953 106992 Y379 E H E D T D K Y R Q L L V R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507656 953 106948 Y379 E H E D T D K Y R Q L L V R T
Chicken Gallus gallus Q5ZIA5 953 107103 Y379 E H E D T D K Y R Q L L V R T
Frog Xenopus laevis NP_001090083 953 106905 Y379 E H E D T D K Y R Q L L V R T
Zebra Danio Brachydanio rerio NP_001002013 953 107075 Y379 E H E D T D K Y R Q L L V R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45437 964 107388 Y376 E H E D T G K Y R Q L L V R T
Honey Bee Apis mellifera XP_001120953 949 104712 Y371 E H E D A G R Y R Q L L V R T
Nematode Worm Caenorhab. elegans NP_494441 971 107512 Y379 S N D E N G K Y R Q E L V K T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SV20 948 106059 Y374 E L E K N G E Y R Q M L I Q A
Baker's Yeast Sacchar. cerevisiae P41810 973 109001 Y380 D Q D K A M Q Y R Q L L I K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 89.6 N.A. 99.2 99 N.A. 97.5 97.9 94.7 93.4 N.A. 67.1 69.7 60.1 N.A.
Protein Similarity: 100 99.7 N.A. 90.1 N.A. 99.7 99.7 N.A. 99.1 99.3 98.1 96.9 N.A. 81.1 82.6 75.8 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 80 46.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 86.6 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.2 42.5 N.A.
Protein Similarity: N.A. N.A. N.A. 70.3 64.3 N.A.
P-Site Identity: N.A. N.A. N.A. 40 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 15 79 0 65 0 0 0 0 0 0 0 0 0 % D
% Glu: 86 0 86 8 0 0 8 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 % G
% His: 0 79 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % I
% Lys: 0 0 0 15 0 0 79 0 0 0 0 0 0 15 0 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 86 100 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 0 15 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 8 0 0 100 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 8 0 100 0 0 0 0 79 0 % R
% Ser: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 72 0 0 0 0 0 0 0 0 0 93 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 86 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _